Project Grant R01AI177367

Award Date 7/23/25
Completion Date 6/30/29
Dollars Obligated $3.1M
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Stony Brook, NY 11794, USA
Similar Awards
This federal Project Grant award of $2,976,652 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to explore polyamine toxicity and resistance in epidemic bacterial skin pathogens, specifically methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes (Group A Streptococcus). The research aims to understand how polyamines enter and kill these bacteria, and how...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $481,250 to The Broad Institute, Inc. to develop antimicrobial compounds that recruit the immune system to target bacteria. The project will involve biochemical, biophysical, and cell biology experiments to characterize chimeric molecules that combine bacterial binders and immune system protein binders. This research aims to create...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $782,178 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Research Foundation for the State University of New York, doing business as Stony Brook University. The grant supports research to develop novel antifungal inhibitors targeting the sterylglucosidase enzymes SGL1 and SGLA, which are essential for the pathogenicity of the fungal pathogens Cryptococcus neoformans and...
The federal Project Grant award R38AI181012, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $225,417.00 to the Icahn School of Medicine at Mount Sinai to establish the Mount Sinai Stimulating Access to Research in Residency (STARR) program. This new initiative aims to reinvigorate the physician-scientist pipeline, particularly in the areas of infectious diseases, allergy, and...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $238,787 to Stony Brook University to conduct research on tracking the secretion of proteins critical for the growth, survival, and virulence of pathogenic mycobacteria like Mycobacterium tuberculosis. The research aims to develop new methods to localize mycobacterial proteins within specific subcellular compartments, in order to elucidate...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to develop real-time detection methods for Staphylococcus aureus transmission in hospital settings. The $3,210,845 award to New York University aims to integrate whole-genome sequencing with weekly colonization sampling to analyze transmission dynamics and create predictive models that can...
This federal Project Grant award, valued at $312,000.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award will support research conducted by the University of Texas Health Science Center at Houston (UTHealth) to develop a single-cell resolution understanding of pathogenesis and antibiotic tolerance in Staphylococcus aureus infections. The research aims to explore the...
The federal Project Grant award R21AI188434, totaling $226,253.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research conducted by The Washington University, a private research institution located in Missouri, to study the modulation of neutrophil-endothelial interactions by the ADAM10 protein and its impact on Staphylococcus aureus infection. The goal is to...
This Project Grant award of $2,841,668.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research focused on understanding how the bacterial enzyme SagB in Staphylococcus aureus (S. aureus) modulates the host immune response and promotes infection. The key goals are to determine how SagB-modified peptidoglycan is recognized by immune cells, investigate the mechanism of SagB-dependent IL-1β...
This federal Project Grant award, valued at $722,026, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research to investigate mechanisms of neuroinvasion, neuroinflammation, and cell senescence that contribute to the severe neurological damage and high mortality associated with Powassan virus (POWV) infection in the elderly. The research aims to reveal age-dependent...

This federal Project Grant award of $3,125,627.00 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to develop new therapeutic strategies that promote enhanced anti-microbial immune responses. The key objectives are to: 1) optimize inhibitors of the STS-1 phosphatase enzyme, which acts as a negative regulator of immune signaling pathways; 2) elucidate the intracellular activities of STS and identify promising inhibitory compounds; and 3) evaluate the role of STS inhibition in vivo and identify inhibitors with efficacy against Staphylococcus aureus infection. The award was granted to the Research Foundation for the State University of New York, doing business as Stony Brook University, and is expected to run from July 2025 through June 2029.

Generated 8/5/25, 6:04 AM