Project Grant R35GM163674
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Texas A&M University System Health Science Center a Project Grant of $420,657 under the Biomedical Research and Research Training program (CFDA 93.859) to support investigator-initiated basic research. The award, effective July 1, 2026, and concluding March 31, 2031, funds research into nanoscale structure and dynamics within nuclear pores and biomolecular condensates. The research...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $429,000 Project Grant to the University of Texas Health Science Center at Houston under the Biomedical Research and Research Training program (CFDA 93.859) on March 6, 2026, with a performance period extending through February 28, 2031. This award funds fundamental research into the mechanisms regulating endoplasmic reticulum-selective autophagy (ER-phagy) during cellular stress conditions. The...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $390,000 through its Biomedical Research and Research Training program (CFDA 93.859) to the University of Texas Health Science Center at Houston for a Project Grant commencing March 1, 2026, and concluding December 31, 2030. This award funds basic biomedical research investigating inter-organelle unfolded protein response (UPR) coordination and cellular proteostasis—specifically examining how cells...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $429,000 Project Grant to the University of Texas Health Science Center at Houston for basic biomedical research on membrane phospholipid homeostasis in microorganisms. Funded through the Biomedical Research and Research Training program (CFDA 93.859), the award commenced on August 1, 2026, and extends through March 31, 2031. The research investigates the structural organization and regulatory...
- Federal Project Grant Award Summary Award Details: Texas A&M Engineering Experiment Station received $394,917 from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859) on July 15, 2026, with completion targeted for March 31, 2031. Products and Services: This Project Grant funds the development of advanced label-free microscopy tools and analytical methods to establish quantitative relationships between cellular...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $451,000 to The University of Texas MD Anderson Cancer Center on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research on ion channel regulation by auxiliary proteins. This project, scheduled for completion by March 31, 2031, applies an integrative research strategy combining quantitative proteomics, electrophysiology,...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $420,476 Project Grant to the University of Texas Health Science Center at Houston under the Biomedical Research and Research Training program (CFDA 93.859) for the period August 1, 2026, through July 31, 2031. The award funds structural and mechanistic studies of eukaryotic gene transcription regulation, specifically investigating how the CDK8 kinase module (CKM)—comprising MED13, MED12, CDK8, and...
- Federal Project Grant Award Summary Texas A&M University received a $785,624 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through June 30, 2028. This award supports the development and application of Bayesian statistical modeling approaches to analyze single-cell spatial transcriptomics data. The research investigates how circadian rhythm disruption (CRD)...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $576,104 to The Regents of the University of California, San Francisco under the Biomedical Research and Research Training program (CFDA 93.859) on August 15, 2025, for a project titled "Molecular Basis for Transmembrane Conduction & Signaling." This five-year project, scheduled for completion by July 31, 2030, supports fundamental research to determine the atomic-level mechanisms...
- Federal Grant Award Summary The University of Texas Health Science Center at Houston received a $423,576 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2026, through April 30, 2031. This award funds the development of a unified, machine learning-driven computational modeling framework designed to advance the interpretation and analysis of cryo-electron microscopy...
The National Institute of General Medical Sciences (NIGMS) awarded Texas A&M University System Health Science Center a $418,952 Project Grant effective September 1, 2026, through April 30, 2031, under the Biomedical Research and Research Training program (CFDA 93.859). The award supports research on molecular control of calcium signaling at membrane contact sites (MCSs)—dynamic inter-organelle interfaces critical to cellular physiology. The research addresses fundamental gaps in understanding endoplasmic reticulum (ER) calcium homeostasis regulation through three integrated research directions: development of light-controlled actuators to manipulate organelle positioning and MCS architecture with high spatiotemporal precision; engineering of genetically encoded, light-sensitive tools to interrogate inter-organellar calcium signaling at defined subcellular locations; and functional characterization of the ER calcium regulatome through high-throughput screening and proximity proteomics. The research aims to deliver reversible, non-invasive, and multiplexed platforms for controlling protein function and calcium dynamics—capabilities currently lacking in existing genetic and pharmacological tools. Project outcomes will be validated across immune, neuronal, and cardiovascular model systems to establish physiological relevance. By integrating real-time imaging, proteomic mapping, and advanced light-responsive technologies, this project seeks to establish foundational tools and knowledge that advance understanding of calcium signaling mechanisms fundamental to metabolism, gene expression, immunity, and neuroplasticity.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $419.0k | 7/7/26 |