Project Grant R35GM161388
- Federal Grant Award Summary The University of Nebraska Medical Center (UNMC) received a $435,372 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective August 13, 2025, with a completion date of July 31, 2027. The award funds development of a novel electrotaxis system designed to enhance chronic wound healing by leveraging...
- The National Institute of General Medical Sciences (part of the National Institutes of Health, Department of Health and Human Services) awarded $393,800 to the Terasaki Institute for Biomedical Innovation on September 5, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop immunomodulatory nanofibrous modular aerogels for chronic wound healing. The research addresses chronic wounds affecting approximately 6.5 million Americans by combining three engineered...
- The National Institute of Allergy and Infectious Diseases awarded $762,758 to the Board of Regents of the University of Nebraska, acting through its University of Nebraska Medical Center division in Omaha, Nebraska, on June 24, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The recipient is developing bioengineered 3D bioprinted scaffolds to treat Staphylococcus aureus biofilm infections following craniotomy procedures. The scaffolds employ two delivery...
- The National Institute of General Medical Sciences awarded the Regents of the University of Michigan $409,941 on March 5, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct research on reprogramming cells for repair of chronic wounds. The research program centers on four investigative questions about how T-cell phenotypes contribute to inflammatory dysregulation in chronic wounds, whether T-cells can be reprogrammed to mitigate inflammation and resolve...
- The National Institute of General Medical Sciences awarded $451,000 to The University of Texas MD Anderson Cancer Center on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to dissect the role of extracellular vesicles and matrix in wound healing. The research identifies mechanisms by which fibroblasts respond to tissue injury through extracellular vesicle cargo packaging and extracellular matrix remodeling. The project uses genetically engineered...
- The National Institute of General Medical Sciences awarded the University of New England $390,500 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to probe cell signaling complexity in wound healing using engineered protein materials. The recipient will investigate how a protein's molecular environment influences its function and how information flows through protein-ligand interactions using engineered proteins and protein-based materials. The work...
- The National Institute of General Medical Sciences awarded the Board of Regents of the University of Nebraska $1,173,748 on July 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support Phase 3 of the Nebraska Center for Integrated Biomolecular Communication (NCIBC). NCIBC advances understanding of biomolecular communication pathways that regulate cellular functions and coordinate intercellular actions, with application to disease mechanisms and targeted...
- Federal Grant Award Summary The University of Nebraska Board of Regents received a $2.04 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded August 8, 2025, with completion targeted for July 31, 2029. This award supports fundamental research investigating the ARP2/3 complex—a critical protein assembly system essential to cellular processes including cell migration, tissue...
- The National Institute of General Medical Sciences awarded $404,831 to the Board of Regents of the University of Nebraska on August 10, 2026, to develop a single-cell transcriptomic atlas for the formation and fate of microbial communities under the Biomedical Research and Research Training program (CFDA 93.859). The research addresses fundamental gaps in understanding how bacteria in microbial communities leverage genetic regulatory systems to coordinate the initiation of cellular heterogeneity...
- The National Institute of General Medical Sciences awarded the University of Wisconsin–Madison $116,005 on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support molecular research on neutrophil reverse migration in wound healing. The award funds the K99 phase of a study examining neutrophil subpopulations and their role in inflammation resolution. The research identifies key neutrophil subpopulations involved in reverse migration, tracks their...
The National Institute of General Medical Sciences awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center division, $415,113 under the Biomedical Research and Research Training program (CFDA 93.859) on September 1, 2026. The award funds development of nanofiber-based sutures and dressings to reduce surgical site infections, treat wound biofilms, and promote chronic wound healing. The research builds on prior findings demonstrating successful encapsulation and sustained release of vitamin D and other immunomodulating compounds to induce antimicrobial peptide expression, efficacy of Janus-type wound dressings in biofilm eradication, and effectiveness of three-dimensional nanofiber scaffolds with patterned macrochannels in wound repair and tissue regeneration, particularly in diabetic wound models when combined with W379 peptides. Performance occurs in Omaha, Nebraska, with a period of performance through June 30, 2031. This is a Project Grant, a standard assistance type under the program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $415.1k | 8/19/26 |