Project Grant R35GM161360
- Federal Project Grant Award Summary The University of Oregon received a $401,285 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective February 24, 2026, through December 31, 2030. This R35 Maximizing Investigators' Research Award (MIRA) supports two distinct research projects investigating the molecular mechanisms of antimicrobial resistance through advanced computational...
- Federal Grant Award Summary The University of Oregon received a $399,227 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, with completion targeted for May 31, 2030. This award supports fundamental research investigating the mechanisms of evolution at the host-pathogen interface, with particular focus on bacterial pathogens of humans. The research integrates...
- Federal Grant Award Summary Oregon State University received a $408,375 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on August 18, 2025, with completion targeted for July 31, 2030. The grant supports fundamental research aimed at uncovering the rules governing the spread of mobile genetic elements (MGEs)—diverse DNA elements such as plasmids and integrative and conjugative elements...
- Federal Project Grant Award Summary The University of Oregon received a $398,464 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 6, 2026, with a completion date of December 31, 2030. This R35 award supports a five-year research initiative focused on developing innovative chemical tools and strategies to modulate reactive sulfur species (RSS), including hydrogen sulfide...
- Federal Grant Award Summary The University of Florida's Division of Sponsored Research received a $680,790 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025, through May 31, 2030. This award supports fundamental research to elucidate gene function through comparative genomic and experimental approaches, addressing a critical gap in the post-genomic era where approximately...
- Federal Grant Award Summary The University of Oregon received a $1.76 million Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2025, through May 31, 2030. This award funds the establishment of a Social Microbiome program to conduct fundamental research investigating how microbial communities assembled through social interactions impact host health and sociality. The...
- Federal Project Grant Award Summary The University of Virginia received a $415,171 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 15, 2026, with completion targeted for February 28, 2031. This Maximizing Investigators' Research Award (MIRA) funds the development and characterization of the first photopatterned hydrogel 3D cell culture platform capable of...
- Federal Grant Award Summary The University of Missouri System received a $357,666 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), awarded July 1, 2025, with completion targeted for May 31, 2030. This five-year research initiative will advance understanding of DNA-manipulating enzyme dynamics through the development and application of single-molecule biophysical measurement techniques, including...
- Federal Grant Award Summary Northwestern University's Sponsored Research Division received a $440,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025 through May 31, 2030. This Maximizing Investigators' Research Award (MIRA) supports fundamental research investigating how the epitranscriptome—the collection of chemical modifications on RNA molecules—regulates...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded the University of Virginia $444,125 under the Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on protein sorting and localization to cellular organelles. The project, which commenced August 1, 2025, and extends through June 30, 2030, will deliver scientific research outputs focused on elucidating the molecular mechanisms governing protein import and...
The University of Oregon received a $403,836 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026 through February 28, 2031. This Maximizing Investigators' Research Award (MIRA) supports a collaborative five-year research program conducted by Professors Andrew H. Marcus and Peter H. Von Hippel at the University of Oregon's Institute of Molecular Biology in Eugene, Oregon. The award funds fundamental research investigating DNA "breathing" fluctuations and their molecular mechanisms in bacteriophage T4 DNA replication complexes, utilizing advanced single-molecule fluorescence and ensemble spectroscopic methods to analyze DNA conformational dynamics and microsecond-resolved fluctuations. The research program represents a continuation of established collaborative work between the Marcus and Von Hippel laboratories, succeeding a previous R01 grant (GM15792) that concluded in 2026. The project employs site-specifically fluorescently-labeled DNA constructs to determine local conformations and conformational disorder at biologically relevant positions, with the goal of developing insights into human DNA replication mechanisms and providing foundational understanding of molecular defects underlying genetic diseases. The research outcomes will contribute to basic knowledge of macromolecular replication machines relevant to human genome expression and disease pathogenesis.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $403.8k | 2/27/26 |