Project Grant R35GM159982
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $413,300.00 to the University of Southern California (USC) to conduct research in three critical areas of human genetics. The funded research will: Model recessive selection on complex traits by leveraging X chromosome data to better understand the strength of selection across different traits and diseases. Explore...
- The National Institute of General Medical Sciences (NIGMS) awarded a 5-year, $616,786 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Regents of the University of California, San Francisco (UCSF) to conduct research aimed at uncovering how evolutionary forces shape patterns of genetic variation and drive phenotypic variation across human populations. The research focuses on three key areas: 1) exploring the effects of recessive deleterious alleles...
- This federal Project Grant award of $423,750.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant, awarded on May 1, 2025, supports a research project at New York University (NYU) School of Medicine to develop new conceptual and statistical approaches that integrate molecular, cellular, and population genetics to better understand the genetic basis of complex human traits and diseases....
- This $780,113 Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) aims to develop methods for quantifying and correcting biases in the genetic study of complex traits. Specifically, the research will: Create a comprehensive simulation framework to model realistic intergenerational dynamics and understand genetic transmission across generations. This will help correct biases in current methodologies used to study genetic architecture....
- This $2,409,233 federal Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) supports the development of a suite of advanced statistical tools and user-friendly software to enhance the accuracy and reproducibility of single-cell and spatial omics data analysis. The key products and services to be delivered under this 4-year award include: Statistical methods to generate in silico data for use as negative controls and pseudo-replicates of...
- This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) is focused on developing and applying machine learning-based approaches to estimate disease risk in diverse and admixed populations. The $399,156 award to Galatea Bio Inc., a minority-owned small disadvantaged business located in Miami Lakes, FL, will support the following key objectives over the project period from September 2024 to August 2025: Evaluating the performance of existing...
- This $346,582 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support the development of novel statistical and computational methods for genetic epidemiology. The key products and services to be delivered under this 5-year award include: Efficient coalescent-based phylodynamic methods to jointly infer genealogies and model parameters from pathogen genetic data, incorporating...
- This Project Grant award from the National Science Foundation (CFDA 47.075 - Social, Behavioral, and Economic Sciences program) provides $277,956 to The Regents of the University of Colorado to assess the presence and impact of archaic hominin ancestry in modern human populations with complex population histories. The study applies sophisticated computational genetic techniques to existing information to separate archaic ancestry contributions from those derived from modern groups, examining the...
- This Project Grant award of $666,831 was provided by the National Human Genome Research Institute (NHGRI) under the Human Genome Research federal grant program (CFDA 93.172). The grant supports the development of new Bayesian techniques to estimate the magnitude and direction of gene effects on traits using rare protein-coding variants, including loss-of-function mutations, deletions, and duplications. The goal is to improve the assessment of gene importance for understanding the molecular basis...
- This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) provides $196,296 to the University of Chicago to conduct research on the relationship between genetic relatedness and phenotypic covariance. The key objectives are to: 1) Understand how methodological details in computing genetic relatedness matrices may bias heritability estimates at different levels of relatedness, and 2) Develop quantitative genetic models that consider the...
This federal Project Grant award, valued at $395,200.00 and provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research by the University of Southern California (USC) to develop novel computational methods for inferring complex demographic histories and detecting deleterious genetic variation across global human populations. The key products and services to be delivered under this 5-year award, which began on September 1, 2025, include: This research aims to provide the genomics research community with enhanced tools and insights to better understand human evolutionary history, population genetics, and the genetic basis of disease.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $395.2k | 8/22/25 |