Project Grant R35GM159944
- This federal Project Grant award of $382,755.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the mechanisms underlying circadian gating of stress responses in plants. The project aims to leverage the Arabidopsis plant model and a combination of genetic, genomic, biochemical, and molecular biology approaches to identify key regulators involved in how the circadian...
- This $380,089.00 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports fundamental research on the molecular mechanisms underlying circadian rhythms. The project aims to determine the mechanisms that define the period and light-dependent phase shift of circadian rhythms, which are critical for aligning cellular and physiological processes with external environments. By...
- This $574,021 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to advance the scientific understanding of the molecular interconnections between circadian rhythms and lipid metabolism. The research project, led by the University of Missouri System, will investigate three key knowledge gaps: 1) how phosphatidic acid (PA) mediates nuclear processes, 2) how PA and lipid...
- The National Institute of General Medical Sciences (NIGMS) awarded a $435,126 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Chicago. The grant, titled "Connecting Circadian Clock Dynamics to Metabolism and Fitness," will support research to understand the biophysical basis of circadian rhythms and their connection to metabolism, with the goal of recreating an oscillatory system using purified components. Key activities...
- This federal Project Grant award of $1,115,181.00 from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program will support research by The Washington University in University City, Missouri to investigate the role of biomolecular condensates in nutrient signaling and epigenome dynamics in Arabidopsis plants. The goal is to enhance understanding of how plants use these microscale compartments to sense their environment and reprogram their epigenomes to...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $123,795 to The Salk Institute for Biological Studies to conduct research on reversing the effects of severe stress in plants. The research aims to generate comprehensive datasets on the transcriptional programs involved in plant stress recovery, focusing on understanding the role of epigenetic changes and key regulatory genes...
- This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $750,000 to the University of Missouri System from January 1, 2023 through December 31, 2026. The grant supports collaborative research among multiple institutions to elucidate the genetic and molecular mechanisms underlying nonhost resistance in plants. Nonhost resistance confers broad immunity to most plant species against pathogens that can infect other species. The research aims to...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $416,050 to The Washington University in University City, Missouri to conduct research on understanding the metabolic and regulatory control of antibiotic production in filamentous actinobacteria. The research aims to investigate two families of antibiotic molecules - polycyclic tetramate macrolactams and...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $392,812.00 to Texas A&M University to conduct research on the effects of circadian rhythm disruption on the mammary microenvironment. The researchers will leverage spatial transcriptomics and Bayesian modeling approaches to investigate how disruptions to the body's 24-hour cycle impact cellular activities and...
- This $1,242,385 National Science Foundation Project Grant under the Biological Sciences program (CFDA 47.074) funds research at the University of Missouri System to coordinate plant responses to abiotic and biotic stresses. The research aims to understand how plants prioritize and integrate signals from diverse environmental stresses like low nutrient availability and bacterial pathogens. A team of researchers with expertise in iron nutrition, bacterial pathogen responses, cellular biology,...
This federal Project Grant award of $2,138,125 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports a research program at Washington University in University City, Missouri focused on understanding how natural circadian rhythms influence immune responses in plants. The research aims to leverage the genetic diversity of Solanum plant species to study the interaction between circadian rhythms and immunity, with the goal of identifying key genetic factors and regulatory networks that govern circadian-mediated immune responses. The 4-year project will utilize a multi-method approach, including laboratory experiments and bioinformatics analyses, to deepen the understanding of how environmental factors like light, temperature, and humidity impact biological rhythms and circadian-mediated immunity in plants. The insights gained could have broader implications for understanding human health and immunity.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.1m | 8/8/25 |