Project Grant R35GM159868
- The National Institute of General Medical Sciences (NIGMS) awarded a $557,900 Project Grant to the Massachusetts Institute of Technology (MIT) under the Biomedical Research and Research Training program (CFDA 93.859). The grant funds a long-term research strategy to study ongoing adaptation and selective forces within human microbiomes. Using a culture-dependent genomic approach, the project aims to characterize within-person evolution over a dozen microbial species found in the skin, vagina,...
- This $388,750 federal Project Grant was awarded on September 19, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to The Washington University in University City, Missouri. The funding will support a 5-year research project to investigate the mechanisms driving host-associated microbial community dynamics, with a focus on understanding how environmental and host factors interact to shape gut microbiome...
- This federal Project Grant award of $361,416 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research by Arizona State University (ASU) on the mechanisms of mammal-microbial coevolution and its implications for host health. The research aims to: 1) Identify codiversified microbial taxa and traits across various body sites and populations of Peromyscus deer mice; 2) Investigate whether host...
- This federal Project Grant award for $353,500.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the impact of xenobiotic exposure on the gut microbiome and its resilience against gastrointestinal pathogens. The research program aims to fill a critical knowledge gap by examining how xenobiotics and their biotransformation products affect the composition, metabolism,...
- This $421,250 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support research to elucidate how lifestyle factors such as diet, exercise, and social interactions shape the gut microbiome's contributions to human metabolic health. Over the 5-year grant period from September 2025 to June 2030, the research will be conducted by the President and Fellows of Harvard College. The...
- This federal Project Grant award of $914,479 from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund a research project led by The Trustees of Columbia University in the City of New York to study the spatial organization and stability of synthetic gut microbiome communities in gnotobiotic mice. The research aims to elucidate the principles governing the assembly and persistence of microbial communities in the human digestive tract, which are essential for human...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $422,931.00 to the University of Colorado-Denver to characterize how specialized microbial metabolites mediate interactions within the human microbiome. The research aims to elucidate the role of these metabolites in enabling microbial communities to resist antimicrobial therapies, with the goal of improving...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $1,759,395 Project Grant to the University of Oregon to investigate the hypothesis that "social microbiomes are major drivers of host health and sociality." The proposed research will use a zebrafish model to study how social interactions shape the microbiome, and how these "social microbiomes" impact host development, behavior,...
- This federal Project Grant award of $395,701.00 was provided by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), to the University of Texas at Austin. The funding supports a research program to study the molecular bases of interactions between bacteria and between bacteria and their animal hosts, with a focus on insect microbiomes. The key objectives are to understand: 1) how competitive interactions between...
- This NSF Biological Sciences (CFDA 47.074) Project Grant award of $600,000 to Emory University will investigate how microbiome communities, which are communities of bacteria and other microbes that live in and on organisms, can resist change and transition to alternate states. The project will use the nematode worm Caenorhabditis elegans as a model host to better define the stability and properties of alternate microbiome states, as well as how factors like antibiotic treatment and host...
This Project Grant award of $2,095,736.00, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project investigating the response of the commensal gut microbiota to host physiological stress. The award, provided to the University of Arizona, aims to utilize a novel non-model rodent system, free-living North American red squirrels, to identify the molecular mechanisms underlying microbial responses to host stress and determine the specificity and scope of these responses. The project, spanning from September 5, 2025 to September 4, 2029, will employ a series of controlled experimental manipulations to induce and study the effects of host stress on the gut microbiota, with the goal of advancing the understanding of how host-microbiome interactions contribute to complex disease.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.1m | 9/5/25 |