Project Grant 2522218
- This federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) in the amount of $300,000 supports research by Duke University to develop an integrated experimental and computational approach to uncover the design principles governing microbiome function. The key objectives are to apply advanced machine learning techniques, high-throughput microbial community construction, and metabolomics to elucidate the molecular networks and cellular...
- The National Science Foundation awarded a $996,521 project grant under the Biological Sciences program (CFDA 47.074) to the Carnegie Institution of Washington for the period of April 1, 2021 through March 31, 2024. The goal of the research project is to scale single-cell physiology studies to better understand community stability in the natural gut microbiome. As part of this work, Johns Hopkins University will expand its microbiome curriculum to additional middle schools in Baltimore County...
- This $985,496 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research by the University of Rochester to develop an innovative platform for controlling and stabilizing microbial communities. The project aims to leverage horizontal gene transfer, specifically through plasmid conjugation, to dynamically balance growth rates and community composition, creating programmable microbial populations capable of maintaining stability across...
- This NSF Biological Sciences (CFDA 47.074) Project Grant award of $600,000 to Emory University will investigate how microbiome communities, which are communities of bacteria and other microbes that live in and on organisms, can resist change and transition to alternate states. The project will use the nematode worm Caenorhabditis elegans as a model host to better define the stability and properties of alternate microbiome states, as well as how factors like antibiotic treatment and host...
- The Project Grant award, titled "Simplifying the Description, Not the System: Advanced Ecological Theory for Real-World Microbiomes", is funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). Over the 5-year period from September 1, 2025 to August 31, 2030, the $326,550 grant will support research at The Washington University in University City, MO to develop computational tools and statistical...
- The National Institute of General Medical Sciences (NIGMS) awarded a $557,900 Project Grant to the Massachusetts Institute of Technology (MIT) under the Biomedical Research and Research Training program (CFDA 93.859). The grant funds a long-term research strategy to study ongoing adaptation and selective forces within human microbiomes. Using a culture-dependent genomic approach, the project aims to characterize within-person evolution over a dozen microbial species found in the skin, vagina,...
- The National Science Foundation awarded a $276,000 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to support a postdoctoral fellowship in biology from September 1, 2022 to August 31, 2024. The fellowship will fund the collection and analysis of gut microbiome samples from over 3,300 animal species, representing the most comprehensive dataset to date. This will allow for improved understanding of the origins and ecological controls of gut microbiomes across the...
- This $763,538 federal Project Grant was awarded to the University of Chicago on July 15, 2024 by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074). The project aims to understand the mechanistic basis of functional robustness in the soil microbiome, connecting detailed microbial processes to broader ecological and environmental outcomes like soil fertility and greenhouse gas emissions. The research objectives include elucidating how soil microbiomes respond to...
- This National Science Foundation (NSF) Project Grant award under the Biological Sciences program (CFDA 47.074) provides USD 270,000 in funding from August 1, 2025 to July 31, 2028. The award supports a Postdoctoral Research Fellowship focused on deciphering the role of pyrazine biosynthetic enzymes in host-colonization dynamics and gut chemical diversity within the gut microbiome. The research aims to increase understanding of how microbial communication influences colonization of the host gut...
- This federal Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to define molecular mechanisms underlying the gut microbiome's ability to resist colonization by pathogens like Vibrio cholerae. The $2,065,745 grant, awarded to the Regents of the University of California at Riverside, aims to provide a mechanistic understanding of how the biochemical environment of...
This federal Project Grant award of $914,479 from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund a research project led by The Trustees of Columbia University in the City of New York to study the spatial organization and stability of synthetic gut microbiome communities in gnotobiotic mice. The research aims to elucidate the principles governing the assembly and persistence of microbial communities in the human digestive tract, which are essential for human health, environmental processes, and biotechnology applications. Using a defined synthetic gut microbiome model, the project will employ high-resolution spatial metagenomics, functional genomics, and biofilm characterization to investigate how spatial organization and biofilm formation impact the resilience of these communities under changing conditions such as diet. The findings are expected to establish a framework for understanding microbial ecosystems that could be broadly applicable. The project has a period of performance from September 1, 2025 to July 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $914.5k | 8/28/25 |