Project Grant R35GM158157
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $451,250.00 to Children's Hospital Medical Center in Cincinnati, Ohio to investigate the molecular basis of circadian and sensory integration in neuronal clocks. The research aims to understand how gene expression in brain oscillators is affected when clock gene rhythms are disrupted in the suprachiasmatic nucleus,...
- The National Institute of General Medical Sciences (NIGMS) awarded a $597,573 Project Grant under CFDA 93.859 - Biomedical Research and Research Training to The Ohio State University (OSU) with a project period from Jun 1, 2025 to Mar 31, 2030. The grant supports fundamental scientific research and advanced training focused on understanding the structure, dynamics, interactions, and function of large protein and protein-nucleic acid complexes that play key roles in human health and disease....
- This $380,089.00 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports fundamental research on the molecular mechanisms underlying circadian rhythms. The project aims to determine the mechanisms that define the period and light-dependent phase shift of circadian rhythms, which are critical for aligning cellular and physiological processes with external environments. By...
- This federal Project Grant award of $382,755.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the mechanisms underlying circadian gating of stress responses in plants. The project aims to leverage the Arabidopsis plant model and a combination of genetic, genomic, biochemical, and molecular biology approaches to identify key regulators involved in how the circadian...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $361,454.00 in funding to the University of Massachusetts Boston to investigate the molecular mechanisms underlying circadian compensation in eukaryotic organisms. The overarching objectives are to: 1) define cellular effectors and metabolic variables that control circadian oscillations in fungi and test for...
- This $381,801 project grant award from the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training) will fund research at the University of California, Santa Cruz to gain insights into how biological timers control development and how the apical extracellular matrix is constructed and remodeled in the nematode model organism C. elegans. The research aims to understand the properties, components, and regulation of developmental timers that synchronize...
- The National Institute of General Medical Sciences (NIGMS) awarded a $1,399,125 Project Grant to The Regents of the University of California, doing business as the University of California, Berkeley, under the NIGMS Biomedical Research and Research Training program (CFDA 93.859). The grant aims to decode the molecular processes that regulate circadian rhythms in malaria parasites and discover how disrupting their regulatory networks impacts malaria pathogenesis and transmission. The project will...
- This $574,021 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to advance the scientific understanding of the molecular interconnections between circadian rhythms and lipid metabolism. The research project, led by the University of Missouri System, will investigate three key knowledge gaps: 1) how phosphatidic acid (PA) mediates nuclear processes, 2) how PA and lipid...
- This federal Project Grant award of $837,277, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research at Vanderbilt University to elucidate the fundamental cellular and molecular mechanisms of circadian entrainment and plasticity. The research aims to advance the understanding of how gene networks give rise to physiology, function, and behavior, with a focus on the brain's endogenous...
- The project grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $249,000.00 to The Ohio State University to study the molecular mechanisms regulating protein synthesis during cell growth and division. The research aims to determine how the concentration of the cell cycle regulator Rb is controlled and how global protein synthesis rates are modulated as cells progress through the cell...
This $2,130,924 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports fundamental scientific research on the regulation of biological oscillators and rhythmic molecular and morphological processes at The Ohio State University. The project aims to advance understanding of the developmental regulation of oscillatory gene expression and protein activity, with a focus on the segmentation clock that controls vertebrate embryonic development. The 4-year award period runs from September 1, 2025 to August 31, 2029 and will fund innovative, interdisciplinary research to elucidate the mechanisms underlying the precise timing and coordination of key biological processes.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.1m | 8/8/25 |