Project Grant R00GM147351
- This $2,130,924 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports fundamental scientific research on the regulation of biological oscillators and rhythmic molecular and morphological processes at The Ohio State University. The project aims to advance understanding of the developmental regulation of oscillatory gene expression and protein activity, with a focus on the...
- The National Institute of General Medical Sciences (NIGMS) awarded a $597,573 Project Grant under CFDA 93.859 - Biomedical Research and Research Training to The Ohio State University (OSU) with a project period from Jun 1, 2025 to Mar 31, 2030. The grant supports fundamental scientific research and advanced training focused on understanding the structure, dynamics, interactions, and function of large protein and protein-nucleic acid complexes that play key roles in human health and disease....
- This federal Project Grant award of $454,367.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to North Carolina State University. The award supports research to determine the mechanisms that govern force production during cytokinesis, the process of cell division. The research aims to reveal how the contractile ring, composed of actin filaments and myosin, generates the forces needed to...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 - Biomedical Research and Research Training program, provides $438,629 to the University of Massachusetts to characterize fundamental and conserved mechano-molecular mechanisms of cell division. The research aims to advance understanding of: 1) the functional contributions of extremely large intrinsically disordered regions (ELIDRs) in proteins at the kinetochore and perichromosomal...
- This $316,968 federal Project Grant was awarded on June 1, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports fundamental scientific research and advanced training focused on understanding the regulation, inhibition, and quality control mechanisms of ribosomes, which are the cellular machinery responsible for protein synthesis. The key research areas include translation fidelity,...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $421,999 in funding to Emory University from July 1, 2025 through April 30, 2030. The award supports research to investigate how posttranscriptional mechanisms, such as local RNA, direct centrosome activity and function. The research aims to determine the basis for cell cycle-dependent oscillations in RNA...
- This federal Project Grant award of $125,000.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to New York University School of Medicine. The research project aims to elucidate the role of the cyclin D1-CDK4/6 complex in regulating protein homeostasis, with a focus on understanding how cyclin D-dependent phosphorylation modulates key effectors of the endoplasmic reticulum-associated...
- This $502,986 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will fund research at Oakland University to investigate the role of cell cycle regulators in mature, non-dividing skeletal muscle cells. The research aims to explore how cell cycle proteins regulate ribosome production and muscle cell size in these postmitotic cells. The project will utilize genetically modified mouse models to manipulate the cell cycle and study its effects...
- This federal Project Grant award, valued at $372,880 and issued on May 1, 2025, is funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports a research project aimed at understanding how cells regulate protein synthesis to maintain homeostasis during cellular stress. The key focus is on investigating the role of the translation initiation factor eIF2 and its phosphorylation in modulating gene...
- This Project Grant award of $254,919.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research at the University of California, San Diego (UCSD) to investigate the regulatory mechanisms that ensure accurate transmission of the genome during cell division. Specifically, the research aims to study how post-translational modification enzymes regulate the assembly and function of DNA replication...
The project grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $249,000.00 to The Ohio State University to study the molecular mechanisms regulating protein synthesis during cell growth and division. The research aims to determine how the concentration of the cell cycle regulator Rb is controlled and how global protein synthesis rates are modulated as cells progress through the cell cycle and change in size. This work is expected to enhance understanding of the linkages between cell growth and cell division, which are critical processes for tissue homeostasis, regeneration, and cancer development. The grant period runs from September 1, 2025 to August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.0k | 7/25/25 |