This $317,629 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research by the Trustees of Indiana University to elucidate the neuronal basis of sexual dimorphism in the Drosophila circadian system. The project aims to understand how differences in the architecture of the circadian system in the Drosophila brain underlie sex differences in sleep/wake cycles and timekeeping robustness. Key research activities include...
This federal Project Grant award of $361,454.00 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports research to investigate the mechanisms underlying nutritional compensation in the circadian clock across fungal and mammalian systems. The key objectives are to: 1) define cellular effectors and metabolic variables that control circadian oscillations in fungi and test for conservation in human cells, and 2)...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 - Biomedical Research and Research Training Program provides $438,915 to Florida State University to conduct research on the genetic basis of circadian rhythms and sleep disorders. The key objectives of this 5-year award include: Identifying and characterizing pathogenic mutations in human clock genes that can cause alterations in chronotypes and sleep disorders through a novel...
This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859), supports research to mechanistically understand how circadian and metabolic rhythms shape the functional maturation of fully differentiated cells. With total funding of $406,250 from June 2025 to April 2030, the research aims to: 1) Determine how circadian clock transcription factors program, synchronize, and entrain...
This $179,703 Project Grant was awarded on September 10, 2024 by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859). The grant supports a research project titled "DISEASE GENE DISCOVERY BY MARKOVIAN GENE NETWORK" to be conducted by Rutgers, The State University in New Brunswick, New Jersey. The award will fund the university's research and development efforts to advance understanding in areas such as...
This federal Project Grant award, numbered R35GM156525, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The $507,000 award supports research to investigate two main types of transcriptome evolution in Drosophila species. The first focus is on identifying novel transcriptome elements in Drosophila melanogaster, particularly in reproductive tissues, and examining their functions using CRISPR and...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $451,250 in funding to Childrens Hospital Medical Center in Cincinnati, Ohio. The purpose of this 5-year grant, with a performance period from May 2025 to March 2030, is to investigate the mechanisms that coordinate circadian clock gene expression in brain regions that regulate physiology and behavior. Specifically, the research...
This $1,000,000 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) will support research at West Virginia University to explore circadian regulation of olfactory modulation through serotonin signaling in fruit flies. Over a three-year period, the grantee will combine neuroanatomy, molecular biology and physiology experiments to determine how the brain's clock network influences two identified serotonin neurons that project to multiple processing...
This $1,570,000 Project Grant was awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859). The grant supports research conducted by Rutgers, The State University in Piscataway, NJ to investigate the biochemistry and function of a novel histone modification, H3K23me3, and how the C. elegans germline distinguishes self and non-self small interfering RNAs (siRNAs). The research aims to advance the...
This National Science Foundation (NSF) Project Grant, under the Biological Sciences program (CFDA 47.074), provides $240,000 in funding from February 1, 2024 to January 31, 2027 to support a postdoctoral research fellowship focused on investigating a novel circadian time-keeping mechanism revealed by environmental manipulation. The research plan aims to identify the location in the brain and the mechanism of a non-canonical clock that can rescue daily rhythms in mice with disrupted central clock...