Determining the mechanisms of extracellular vesicle release, function, and clearance
Active Project Grant Awarded Last action
- Award ID
- R35GM152234
- Recipient
-
Texas A&M Agrilife Research UEI KU3DCFJJTVN3 Part of Texas A & M University System
- Awarding agency
-
National Institute of General Medical Sciences
National Institutes of Health, Department of Health and Human Services
- Obligated
- $1,474,306
Award facts
- Assistance listing
- 93.859 Biomedical Research and Research Training
- Completion date 43% complete
- Place of performance
- College Station, TX, USA
Award details come from USAspending.gov.
Description
- Abstract
- Cells release extracellular vesicles (EVS) that carry signals to alter cell fate or metabolism, promote invasive behavior, or modulate the immune response. EVS show great potential as diagnostic biomarkers for disease progression, especially in inflammation and cancer. EVS also show promise as a platform for targeted drug delivery, given their ability to signal to and be taken up by cells. Furthermore, EVS can be degraded via phagocytosis, providing metabolites to the engulfing cell. Despite the interest in EVS, basic cell biological knowledge about EV biogenesis, targeting, cargo transfer, and in vivo function is lacking, largely due to the challenges of imaging
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $369,340 | |
| Amendment | $370,086 | |
| Amendment | $0 | |
| Amendment | $367,440 | |
| Original award | $367,440 |
Quick answers
Who received award R35GM152234?
R35GM152234 was awarded to Texas A&M Agrilife Research by National Institute of General Medical Sciences (National Institutes of Health) on September 5, 2024.
How much is award R35GM152234 worth?
$1,474,306 has been obligated on R35GM152234.
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