This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to The Children's Hospital Corporation, doing business as Boston Children's Hospital, supports research to identify genes and pathways that are suppressed during early tumor development, enabling cancers to evade immune surveillance. The $901,205 award, which began on Jul 3, 2025 and runs through Jun 30, 2032, will leverage genetically engineered mouse models and advanced genomic and spatial analysis techniques to map tumor immune editing processes across a variety of cancer types. The goal is to better understand how tumors suppress both adaptive and innate immune responses, with the aim of identifying novel drug targets that could reverse immune evasion and restore anti-tumor immunity. The research findings could help improve the efficacy of cancer immunotherapies for solid tumors.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $901.2k | 7/3/25 |