Project Grant R34NS143694
- The Project Grant award of $254,250 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research at New York University School of Medicine to develop genetic approaches for studying the organization and function of neocortical layer 1. This research aims to enhance understanding of how top-down and bottom-up information streams are integrated in the brain,...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York, doing business as the Health Sciences Division, a $2,554,313 federal Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). The grant, which runs from Sep 1, 2023 to Aug 31, 2026, will support research to determine if targeted in vivo manipulations of local circuit control...
- This federal Project Grant award of $141,102 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative program (CFDA 93.372). The award supports research by New York University to study the role of astrocyte networks in facilitating neuroplasticity. Key objectives include mapping functional astrocyte networks across the brain using a novel biotinylation...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides $828,335 to the University of Chicago to investigate the roles of inhibitory and disinhibitory neural circuits in the formation, stabilization, and competition of neural assemblies in the cortex. The project aims to experimentally test theoretical...
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
- This federal Project Grant award for $1,042,170.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to apply computational modeling to the analysis of intracranial recording and stimulation data from the human brain. The key objectives are to 1) dissect the neural activity patterns underlying electrophysiology recordings, and 2)...
- This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
- This federal Project Grant award of $401,000.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to map and model multiscale lateral interactions in the cerebral cortex that are critical for processing complex sensory information. The project aims to directly probe local lateral interactions in cortical circuits, determine...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $673,581 to New York University (NYU) to study the dynamics of the cortical-hippocampal circuit and its role in statistical learning. The goal is to build a mechanistic neurobiological circuit theory of statistical learning, which is a fundamental cognitive process enabling the...
- This federal Project Grant award of $459,000.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to understand the anatomical and physiological changes accompanying neocortical malformations known as molecular layer heterotopia (MLH). The research will utilize GPR56 knockout mice to study the neuronal and glial changes in MLH using spatial...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides $381,375.00 to New York University to develop genetic strategies to study a novel disinhibitory system in the cortex. Specifically, the project aims to gain a detailed understanding of how top-down and bottom-up signals are integrated in the superficial layer 1 (L1) of the neocortex, which is a major target for higher-order cortical and thalamic projections carrying information on behavioral saliency, expectations, and memories. This research has significant medical relevance, as disruptions in this signal integration are thought to underlie neurocognitive disorders such as autism and schizophrenia. The project period runs from August 4, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $381.4k | 8/4/25 |