Project Grant R34DA059770
- This Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $844,475 to the University of Alabama at Birmingham (UAB) to test a bundled intervention aimed at increasing treatment uptake for patients with opioid use disorder (OUD) and nonfatal opioid overdoses after emergency department (ED) discharge. The proposed intervention combines telehealth, peer support, buprenorphine prescribing, and linkage to...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), totaling $444,826, is focused on adapting and testing an innovative, trauma-informed intervention to reduce overdose risk among women re-entering the community from prison. The key activities include: 1) Adapting the Trust-Based Relational Intervention (TBRI) approach by engaging stakeholders to align it with the unique needs of justice-involved women,...
- This Project Grant award of $189,500 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to determine the extent of cardiovascular disease (CVD) among people with opioid use disorder (OUD) and explore ways to prevent CVD in this population. The key objectives are to: 1) examine the relationship between CVD and OUD using Transformed Medicaid Statistical Information System data, and 2) assess the impact of Medicaid Health Homes...
- PEACE Platform Development and Evaluation Biomotivate LLC received $613,744 under a Project Grant from the National Institute on Drug Abuse (NIDA) Drug Use and Addiction Research Programs (CFDA 93.279), awarded August 1, 2025, with completion targeted for July 31, 2026. The award funds development and evaluation of the PEACE Platform (Personalized Evocative Audiovisual Content for Everyone), a precision medicine tool designed to complement existing opioid use disorder (OUD) treatment...
- The National Institute on Drug Abuse (NIDA) awarded a $2,729,018 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Rhode Island. The purpose of this 2-year award, with a start date of September 15, 2024, is to rigorously develop and evaluate a mobile health intervention for adults with co-occurring opioid use disorder (OUD) and post-traumatic stress disorder (PTSD) during community re-entry after residential OUD treatment. The proposed mobile app...
- The National Institute on Drug Abuse (NIDA) awarded a $188,307 Project Grant to the University of Pittsburgh under the Drug Use and Addiction Research Programs (CFDA 93.279) effective September 1, 2025, through August 31, 2029. This award supports the development and testing of a guided, web-based behavioral treatment intervention that combines Acceptance and Commitment Therapy (ACT) for chronic pain with Mindfulness-Based Relapse Prevention (MBRP) for substance use disorders. The research...
- This federal Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) totaling $945,397 provides funding to the Magee-Womens Research Institute and Foundation, with a sub-award to the University of Pittsburgh, to adapt and evaluate a collaborative care model (CCM) for treating pregnant persons with opioid use disorder (OUD) in low-resource obstetric settings. The key objectives are to: 1) adapt the CCM for rural and low-resource...
- Federal Project Grant Award Summary Massachusetts General Hospital received a $742,500 Project Grant (R34) awarded on July 15, 2025, by the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279). The three-year pilot award funds the development and testing of an innovative tobacco cessation intervention delivered by Peer Recovery Coaches (PRCs) in recovery from both opioid use disorder (OUD) and tobacco use disorder (TUD). The primary deliverables...
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $431,750 to Rutgers, The State University of New Jersey to conduct research on informing national overdose prevention and treatment strategies for high-risk adolescents. The key objectives of this 2-year project are to: 1) estimate the prevalence of adolescent nonfatal drug overdose and identify high-risk demographic and clinical subgroups,...
- Federal Cooperative Agreement Summary New York University School of Medicine received a $1.75M Cooperative Agreement award from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning July 15, 2025, with completion targeted for June 30, 2027. The award funds a stepped-wedge randomized controlled trial (RCT) designed to evaluate the effectiveness of a technical assistance (TA) intervention for preventing overdoses among residents of...
ADDRESSING RACIAL DISPARITIES IN OPIOID OVERDOSE DEATHS USING AN OPEN SOURCE PEER RECOVERY COACH TRAINING AND MULTIMODAL MOBILE HEALTH PLATFORM - PROJECT SUMMARY BLACK AND LATINX PEOPLE WHO USE OPIOIDS (PWUO) BEAR A DISPROPORTIONATE BURDEN OF OPIOID-RELATED OVERDOSE DEATHS. RACIAL DISPARITIES AMONG PWUO ARE EXACERBATED BY PERSISTENT SOCIOECONOMIC AND STRUCTURAL BARRIERS (E.G., STIGMA, LACK OF SOCIAL SUPPORT, HOUSING INSTABILITY) WHICH MAY BE PARTIALLY ADDRESSED USING SCALABLE OPEN- SOURCE SOLUTIONS (E.G., PEER RECOVERY COACHES, MOBILE HEALTH, TELEMEDICINE). WITH NIH SUPPORT, WE HAVE VALIDATED A THEORY-BASED, AI-DRIVEN TEXTING USING NATURAL LANGUAGE PROCESSING IN A PUBLICLY-FUNDED HEALTH SYSTEM TO PROVIDE REAL-TIME RESPONSES TO PATIENT QUERIES COMBINED WITH AUTOMATED TEXTS TO ENHANCE IDENTIFICATION AND ADDRESS PARTICIPANT UNMET SDH NEEDS (E.G., ACCESS TO PEER SUPPORT, HEALTHCARE), AND LINKAGES AND RETENTION IN BUPRENORPHINE TREATMENT PER THE MEDICAL MANAGEMENT MODEL (E.G., PATIENT EDUCATION, SELF-MANAGEMENT). WE HAVE ALSO REFINED AN EVIDENCE-SUPPORTED CULTURAL STRUCTURAL HUMILITY (CSH) TRAINING FOR PEER RECOVERY COACHES (PRCS) THAT GOES BEYOND A SOCIAL DETERMINANTS OF HEALTH (SDH) FRAMEWORK TO ALSO INCLUDE STIGMA REDUCTION, HEALTH HABITUS, AND PATIENT NAVIGATION TO IMPROVE CLINICAL OUTCOMES AND SOCIAL SERVICES USE AMONG PWUO. THIS PROPOSAL AIMS TO ADAPT THE EVIDENCE-SUPPORTED CSH TRAINING TO INTERACTIVE VIDEO MODULES FOR PEER RECOVERY COACHES (PRCS), AND REFINE AN ARTIFICIAL INTELLIGENCE (AI)-DRIVEN TEXTING TOOL TO REINFORCE CORE CSH PRINCIPLES. THE 3-MONTH PILOT RCT WILL TEST AI-DRIVEN CSH-ENHANCED TEXTING TOOL + CSH-TRAINED PRC PROVIDING TELEPHONE-BASED SERVICES COORDINATION (MULTIMODAL INTERVENTION ARM-1) VS. AI-DRIVEN CSH-ENHANCED TEXTING TOOL (INTERVENTION ARM-2) VS. TREATMENT AS USUAL / INFORMATIONAL PAMPHLETS ONLY (CONTROL ARM) AMONG EMERGENCY DEPARTMENT- ENROLLED BLACK / LATINX PWUO (N=150) TO ESTIMATE RATES OF PRC-PWUO CONTACT, AI-DRIVEN TEXTING USE AMONG PWUO, ASSESS POTENTIAL FOR PRE-/POST-INTERVENTION IMPACT ON REDUCTION OF FELT AND/OR ANTICIPATED STIGMA, CLINICAL OUTCOMES (I.E., TIME TO INITIAL RECEIPT OF BUPRENORPHINE), AND SOCIAL SERVICES USE AT 1- AND 3-MONTHS TO OBTAIN INTERVENTION EFFECT SIZES, AND ESTIMATE THE ASSOCIATED COST OF IMPLEMENTING AND SUSTAINING THE MULTIMODAL INTERVENTION (E.G., COST-PER OUD TREATMENT DAYS). THE RE-AIM FRAMEWORK WILL INFORM IMPLEMENTATION OF THIS MULTIMODAL INTERVENTION THAT HAS HIGH PUBLIC HEALTH IMPACT ON COMPLEMENTING THE HHS OVERDOSE PREVENTION STRATEGY (I.E., HARM REDUCTION, OUD TREATMENT, AND RECOVERY SUPPORT) IN A MANNER THAT IS SCALABLE, SUSTAINABLE, AND EQUITABLE USING OPEN-SOURCE SOLUTIONS. OUR TEAM IS UNIQUELY POSITIONED TO OBTAIN DATA THAT WILL INFORM A SUBSEQUENT LARGE-SCALE EFFICACY TRIAL EVALUATING OUR PROPOSED MULTIMODAL INTERVENTION TO INCREASE ACCESS TO BUPRENORPHINE AND SOCIAL SERVICES AMONG BLACK / LATINX PWUO.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $280.5k | 7/25/25 | ||
| Not listed | $0 | 8/27/24 | ||
| Not listed | $0 | 8/21/24 | ||
| Not listed | $226.0k | 6/27/24 | ||
| Not listed | $226.0k | 6/27/24 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
113921S | Research Foundation For Mental Hygiene, Inc. | Project Grant R34DA059770 | $35.9k | 7/1/24 | |
113921S | New York University | Project Grant R34DA059770 | $57.0k | 7/1/24 |