Project Grant R33DA060625

Award Date 5/15/24
Completion Date 4/30/29
Dollars Obligated $1.4M
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
New Haven, CT 06510, USA
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This $791,101 federal Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) supports a 5-year research study titled "STOP (SHARED DECISION MAKING TO TREAT OR PREVENT) HIV IN JUSTICE POPULATIONS". The study aims to develop and evaluate an implementation approach that integrates patient navigators, risk assessments, and patient choice options to improve access to HIV prevention, HIV treatment, and substance use disorder...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the federal Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,260,957 to the Research Foundation of the City University of New York (RFCUNY) to identify preferences and care components for optimizing the delivery of long-acting injectable (LAI) pre-exposure prophylaxis (PrEP) for sexual minority men (SMM) who use methamphetamine. The key products and services to be delivered under this award...
This federal Project Grant award, valued at $2,442,846 and awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), will support the establishment of a California Hub for HIV/STI/SUD Prevention Research with Reentry Populations. The key products and services to be delivered include: Piloting and adapting the Mobile Enhanced Prevention Support (MEPS) intervention, which combines peer mentors, cash incentives, and a mobile app to...
This $1,272,788.38 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will establish the PRIDE-CARES Center to address gaps in substance use disorder (SUD) research and treatment for the sexual and gender minority (SGM) community. The key products and services to be delivered include: Developing a Virtual Patient Engagement Panel (VIP Panel) to actively engage patients, family members, and individuals in...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242, Mental Health Research Grants, provides $1,554,880 to Yale University to expand and integrate a pre-exposure prophylaxis (PrEP) decision aid into sexual and reproductive health (SRH) clinic contraceptive counseling visits. The project aims to increase PrEP access and uptake among cisgender women in the U.S. by optimizing the decision aid's content to cover all available PrEP formulations and...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $2,214,862 to Duke University to optimize and evaluate the efficacy of a co-packaged long-acting injectable (LAI) pre-exposure prophylaxis (PrEP) and buprenorphine (XR-B) intervention for individuals in carceral and community re-entry settings. The study aims to develop the intervention protocol, evaluate implementation strategies to...
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This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $322,302 in funding to Yale University from September 30, 2024 to August 31, 2029. The award aims to support formal coursework, seminars, interdisciplinary mentorship, and research to expand the skills of a sociologist focused on examining strategies to implement medications for opioid use disorder (OUD) as an HIV prevention approach within...
This Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $239,148 to develop and pilot a telehealth program integrated with syringe service programs (SSPs) to improve uptake and retention of pre-exposure prophylaxis (PrEP) and medication for opioid use disorder (MOUD) among people who inject drugs (PWID). The three-year project, which runs from September 15, 2024 to July 31, 2027, aims to address key...
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This $1,393,769 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to develop and assess a patient-centered approach to improve access to pre-exposure prophylaxis (PrEP), antiretroviral therapy (ART), and substance use disorder (SUD) services for persons who use drugs (PWUD) involved in the criminal justice system.

The 5-year study, led by Yale University, will begin with a 1-year pilot in Connecticut to develop and test a menu of patient choice options for accessing PrEP/ART and SUD treatment services, compared to standard patient navigation alone. The pilot will inform a subsequent 4-year, 4-site (Connecticut, Kentucky, and 2 in Texas) hybrid implementation-effectiveness study, which will evaluate patient-level outcomes like accessing clinicians and treatment, as well as system-level implementation outcomes including acceptability, adoption, penetration, sustainment, and costs. This research has the potential to improve engagement in HIV and SUD services for this critically underserved population.

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