Development and clinical evaluation of the capscan gastrointestinal sampling device for metabolomics monitoring
Active Project Grant Awarded Last action
- Award ID
- R33CA260665
- Recipient
-
Envivo Bio Inc. UEI HM9YHWKYNH95
- Awarding agency
-
National Cancer Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $2,359,062
Award facts
- Assistance listing
- 93.393 Cancer Cause and Prevention Research
- Completion date 85% complete
- Originally
- Place of performance
- San Carlos, CA 94070, USA
Award details come from USAspending.gov.
Description
- Abstract
- The goal of this project is to develop the capscan gastrointestinal (GI) tract sampling capsule, and to utilize this device to advance our understanding of gastrointestinal disorders. Capscan is a novel ingestible device with the potential to routinely collect and analyze the microbiota of the GI tract, including the metabolic transformation of food products by GUT microbes. We will develop, bench test and assess the safety, reproducibility, regional specificity of the capscan device on healthy human volunteers. We will then utilize the capscan device in two additional studies to test the effect of a proton pump inhibitor (PPI) on the microbiome and metabolome and to measure the regional differences in the GI tract in patients with small intestinal bacterial overgrowth (sibo) before and after antibiotic treatment. Given the centrality of the GUT to human health, there will likely be additional uses of the capscan technology in monitoring a person's health, eventually making capscan as routine and informative in the practice of medicine as a blood test is today.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $594,530 | |
| Amendment | $569,684 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $597,424 | |
| Original award | $597,424 |
Quick answers
Who received award R33CA260665?
R33CA260665 was awarded to Envivo Bio Inc. by National Cancer Institute (National Institutes of Health) on April 1, 2022.
How much is award R33CA260665 worth?
$2,359,062 has been obligated on R33CA260665.
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