Project Grant R24OD039745
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) under CFDA 93.351 provides $490,145.00 to the University of Massachusetts to produce and validate monoclonal antibodies that can be used to study proteins in mouse, Xenopus, and axolotl animal models. The goal is to develop these critical research tools to enhance rigor and reproducibility in biomedical research using vertebrate animal models. The project will run from May 2025...
- This Project Grant awarded by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $844,954 to New York University School of Medicine to develop "Genomically Rewritten and Tailored Humanized Mouse Models for Various Organ Disorders." The project leverages advanced DNA synthesis and editing capabilities to create genetically engineered mouse models (GREAT-GEMMs) that accurately represent specific human disease phenotypes. These...
- The National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) awarded a $230,250 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to the University of Nebraska Medical Center (UNMC) to develop and characterize new transgenic mouse models expressing red fluorescent protein (RFP)-based genetically encoded indicators. The goal is to make these RFP-based mouse models available to the scientific community to overcome limitations of commonly used green...
- This $259,423 Project Grant award from the National Institutes of Health (NIH) Office of the Director (CFDA 93.351 - Research Infrastructure Programs) supports the development and characterization of a transgenic rat model to investigate the physiological functions of telomerase reverse transcriptase (TERT) alternative splicing isoforms. The award will enable the University of Michigan to generate and phenotype two new transgenic rat models - one expressing a catalytically inactive TERT splice...
- This Project Grant award of $261,017.00 was provided by the National Institutes of Health (NIH) Office of the Director through the Research Infrastructure Programs (CFDA 93.351) to The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. The grant supports the development of a mouse model system for targeted trimming of disease susceptibility loci, which aims to streamline the identification of genes responsible for particular traits or diseases. The proposed approach...
- The University of Rhode Island (URI) Research Office is receiving a $2,727,001 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Abuse and Addiction Research Programs (CFDA 93.279). The grant will fund research to validate a rabbit model of cerebral palsy-induced pain. Key components include: Determining the face validity of the rabbit hypoxia-ischemia model to assess musculoskeletal, nociplastic, and neuropathic pain phenotypes...
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $775,888 to the La Jolla Institute for Immunology to develop a next-generation CRISPR-ready, HLA class I and II transgenic mouse platform. The goal is to create a modular, CAS9-expressing mouse strain from which investigators can generate HLA class I or II transgenic mice for a broad range of disease research, including infection, cancer, autoimmunity, and...
- This $16,000,000 Project Grant award from the National Institutes of Health (NIH) under the Construction Support program (CFDA 93.352) will fund the construction of a new vivarium facility at Ohio University. The vivarium will be part of the Heritage Translational Research Center, a $67 million biomedical research facility that will consolidate and modernize the university's research infrastructure. The new vivarium will replace an outdated facility, expanding total mouse cage capacity by 64%...
- The U.S. Department of Health and Human Services National Institutes of Health (NIH) awarded a $3,999,180 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to The Administrators Of Tulane Educational Fund, doing business as Tulane University. This grant will fund the expansion of indoor-outdoor housing facilities for Tulane's Specific Pathogen-Free (SPF) Macaque Breeding Colony to support HIV/AIDS-related research at the Tulane National Primate Research Center (TNPRC). The...
- The National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) awarded a $1,291,319 Project Grant to The University of Iowa to support innovations in open sharing of monoclonal antibodies for research. The 4-year grant, starting on April 15, 2025, aims to: 1) develop new open-source non-rodent hybridoma methodology, 2) perform antibody validation for large, less well-characterized monoclonal antibody collections to improve model organism research, and 3) further...
The National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) awarded a $776,504 Project Grant on Aug 1, 2025 to the Regents of the University of Michigan to support the "National Center of Rabbit Models for Translational Research". The grant will fund the development and expansion of genetically engineered rabbit models for biomedical research applications over the 4-year project period ending on Jul 31, 2029. The grant aims to leverage the advantages of rabbit models, including their evolutionary closeness to humans, favorable reproduction, and body size similar to human infants, to advance diverse scientific breakthroughs. The funding will enable the generation of over 40 translationally relevant genetically engineered rabbit lines, including whole body knockouts, humanization of disease-associated alleles, and targeted protein knock-ins, which can be utilized by researchers across multiple disciplines.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $776.5k | 7/30/25 |