Enhancing the utility of deer mice as an infectious disease model
Active Project Grant Awarded Last action
- Award ID
- R24AI186970
- Recipient
-
University Of South Carolina UEI J22LNTMEDP73
- Awarding agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Obligated
- $978,149
Award facts
- Assistance listing
- 93.855 Allergy and Infectious Diseases Research
- Completion date 27% complete
- Place of performance
- Columbia, SC 29208, USA
Award details come from USAspending.gov.
Description
- Abstract
- Deer mice (genus peromyscus) are the most abundant mammals in north america. In biomedical research, their most prominent use is in the field of infectious diseases, because they are the natural reservoir of infectious agents such as borrelia burgdorferi which causes lyme disease, for hantaviruses, SIN nombre virus, and sars-COV-2 that caused the covid-19 pandemic. The university of south carolina operates, for more than 40 years, the peromyscus genetic stock center (pgsc) that is charged with the mission of maintaining different stocks of peromyscus, supplying them to outside investigators and exploiting deer mouse- related research. The present proposal addresses 3 major unmet needs of the peromyscus community of researchers that impede the use of deer mice as a model and are related to the poor breeding program that does not enable rapid availability if deer mice to users, the lack of peromyscus-specific antibodies, and the lack of readily access to breeding records for pedigree analyses. Here, we request funds to enhance the utility of deer mice as a model of relevance to niaid's interests by (1) strengthening the breeding capacities of the pgsc, (2) by developing specialized immunological reagents such as peromyscus-specific antibodies, and (3) by curating our electronic databases and rendering them easily accessible to outside users. Plans for the project's sustainability have been developed, and IT is anticipated that upon completion IT will be supported fully by the income generated.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $511,424 | |
| Original award | $466,725 |
Quick answers
Who received award R24AI186970?
R24AI186970 was awarded to University Of South Carolina by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on June 1, 2025.
How much is award R24AI186970 worth?
$978,149 has been obligated on R24AI186970.
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