Project Grant R21OH012949

CALM-OSA Project Grant Award Summary Yale University received a $764,853 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded August 15, 2025, with a completion date of May 31, 2030. The grant supports the CALM-OSA (Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea) research initiative, which investigates the mechanisms underlying treatment response...

This Project Grant, awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), provides $554,766 in federal funding to Rutgers The State University of New Jersey, School of Nursing, for research examining the mechanisms underlying susceptibility to ozone-induced acute respiratory distress syndrome (ARDS). The research, which commenced June 1, 2026, and extends through March 31, 2031, investigates why certain individuals...

Airalux Medical, Inc. received a $306,872 Project Grant award dated September 5, 2025, from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a digital incentive spirometry device designed to improve patient adherence and clinical workflows. The company is engineering a redesigned incentive spirometer that automatically collects user respiratory metrics and displays them on a mobile dashboard for clinician...

Federal Cooperative Agreement Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Medical University of South Carolina a $688,047 Cooperative Agreement on September 1, 2025, to conduct the WINDSURFER trial (WIN Ratio Analysis to Determine a Strategy of Non-Invasive Support for Respiratory Failure in the Emergency Department). This clinical research initiative will extend through August 31, 2031, and addresses a critical gap in emergency care by comparing the effectiveness...

SMILE (Sickle Cell Disease Microbiologic and Immunologic Links to Health) - Respiratory Control Research Project Grant Emory University received a $794,661 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), with an award date of September 19, 2025, and a completion date of June 30, 2030. This research initiative investigates how higher-order brain regions interact with brainstem circuits to produce...

Grant Award Summary Respair, Inc. received a $305,218 Small Business Innovation Research (SBIR) Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 15, 2025, with completion targeted for August 31, 2027. The grant funds development and feasibility assessment of AssuranceET, a novel pediatric endotracheal tube (ETT) designed to replace traditional inflatable balloon cuff mechanisms with...

This $2,623,234 federal Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) supports the development of a wearable multiplex biosensor system to monitor exacerbation risk in patients with chronic obstructive pulmonary disease (COPD). The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center is the prime awardee, collaborating with researchers at the California Institute of Technology...

ENHANCE-O2 Project Grant Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Johns Hopkins University a Project Grant of $753,721 under the Cardiovascular Diseases Research program (CFDA 93.837) effective May 1, 2026 through January 31, 2031. The ENHANCE-O2 project investigates pulse oximeter accuracy and its clinical impact among hospitalized patients with shock and acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The research addresses a critical...

The Medical University of South Carolina received a $3.75M Project Grant award from the National Institute of Nursing Research (CFDA 93.361 - Nursing Research program) effective March 25, 2026, through February 28, 2030, to develop and evaluate RESP-FIT, a multicomponent mobile health intervention for chronic obstructive pulmonary disease (COPD) management in rural populations. The project delivers a home-based respiratory muscle strength training (RMST) program integrated with mobile health...

Smartairway LLC received a Project Grant award of $313,365 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) for the period of August 1, 2025 through July 31, 2027. The company is developing the SmartStylet, an innovative articulating stylet device designed to improve first-pass endotracheal intubation (ETI) success rates during surgical procedures and emergency medical interventions. The device utilizes a uniquely...