This $1,280,102 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) supports the acquisition of a MEDISO NANOSCAN SPECT/PET/CT imaging system for the University of Pittsburgh's In Vivo Imaging Facility (IVIF). This new instrument will replace and upgrade an aging Inveon PET/CT scanner, enabling IVIF researchers to continue conducting molecular imaging studies to visualize metabolic processes, detect and diagnose cancer,...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the CFDA program "Discovery and Applied Research for Technological Innovations to Improve Human Health" (93.286), will fund the development of a novel real-time interactive Positron Emission Tomography (PET) and Ultrasound (US) imaging technology. The goal is to enable interactive PET and US scanning with real-time visualization of molecular contrast fused with US images to...
This Cooperative Agreement award, with a total funding amount of $846,054, was provided by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) under the Research Infrastructure Programs (CFDA 93.351). The award will support the establishment of the MU Rodent Testing Center for Somatic Cell Genome Editing at the University of Missouri System. The key products and services to be delivered under this award include: 1) breeding and maintaining groups of...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $746,895 to the Regents of the University of Minnesota to establish a non-human primate platform in genetically modified pigs. The goal is to engineer a humanized heart in a gene-edited pig that could serve as an alternative organ source for cardiac transplantation. The key products and services to be delivered...
This Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), is focused on enhancing the efficiency of generating human vasculature in a gene-edited pig. The $279,750 award, granted on May 25, 2025, aims to compare the grantee's proven approach using somatic cell nuclear transfer (SCNT) with an alternative approach using in vitro fertilization, zygote gene editing, and blastocyst complementation. The goal...
The National Institute of General Medical Sciences (NIGMS) awarded a $384,896 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Missouri System. The award will fund research to engineer peptide-based biomodulatory materials that can serve as translational platform technologies for various biomedical applications. Specific objectives include using computational and experimental techniques to develop design rules for micellar...
This $300,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports the development of a GMP-compliant E. coli dihydrofolate reductase (EDHFR) vector. This vector will be used to monitor the biodistribution and trafficking of investigational chimeric antigen receptor (CAR) T cell therapies through positron emission tomography (PET) imaging. The goals are to provide a...
This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $240,039 to Baylor College of Medicine to develop a novel mouse model for detecting genome editing events. The project aims to create a more sensitive reporter system based on the Cre-ERT2 recombinase system to improve detection of CRISPR/Cas9-mediated genome editing. This advanced animal model is expected to enable researchers to better evaluate the...
The National Cancer Institute (NCI) awarded a $1,271,498 Project Grant under the Cancer Biology Research program (CFDA 93.396) to the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center (UNMC) Division. The goal of this 5-year award, effective December 19, 2024, is to develop a porcine model of pancreatic cancer that can be used to more efficiently test experimental therapies and medical devices for pancreatic cancer management. Specifically, the...
This federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) under CFDA 93.351 provides $490,145 to the University of Massachusetts to produce and validate monoclonal antibodies that can enhance rigor and reproducibility in research using vertebrate animal models. The goal is to develop antibodies that recognize proteins in diverse animal models like mice, Xenopus, and axolotl to facilitate biomedical research using these...