Project Grant R21HD117817
Award Date
6/1/25
Completion Date
5/31/27
Dollars Obligated
$501K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Washington, DC 20010, USA
Similar Awards
This $1,875,534 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to leverage pediatric functional brain network dynamics to predict developmental outcomes. The award will: 1) Disentangle the relative contributions of sleep stage and age in early brain network development, and 2) Decode sleep stages in existing infant and toddler sleeping state fMRI data. To...
The National Institute of Child Health and Human Development (NICHD) awarded a $189,056 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Neurosant Therapeutics LLC in San Marcos, CA. The goal of the 2-year project is to demonstrate that the expression of the RAI1 gene, which is reduced in Smith-Magenis Syndrome (SMS), can be increased using a pharmacologic approach to correct the underlying transcriptomic defects associated with this neurodevelopmental...
This federal Project Grant award of $4,698,676 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports a longitudinal study on the association between sleep EEG biomarkers and the development of psychopathology in young adults. The research aims to leverage sleep EEG data from a population-based child cohort to study the trajectories of three sleep EEG biomarkers - slow wave activity (SWA), sleep spindle density (SSD), and odds...
This Project Grant award of $567,704.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program will support research to characterize the effects of RAI1 gene deficiency on sleep/wake rhythms and neural network function in a diurnal rodent model of Smith-Magenis Syndrome. The objectives are to determine the role of RAI1 in regulating daily sleep/wake...
This federal Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate neural markers of developmental delays in premature and full-term infants. The $398,115 award to The Children's Hospital Corporation (doing business as Boston Children's Hospital) will chart brain development using electroencephalography (EEG) during well-baby...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $560,641 to Psychogenics Inc., a for-profit contract research organization, to develop an innovative EEG-based drug repurposing platform called eCube. The goal is to create a Drug EEG Signature Analysis (DESA) algorithm that can compare EEG data from animal models of rare diseases against a reference database of drug EEG signatures to rapidly...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund research to investigate the relationship between sleep, motor learning, and motor development in early childhood. The award of $153,512 will support a 2-year fellowship to achieve two key aims: 1) identify sleep EEG markers that predict motor memory consolidation in 4-year-old children, and 2) examine...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $357,876 to Duke University to develop and utilize electrophysiological and behavioral biomarkers for improving social engagement in individuals with autism. The key objectives are to: 1) validate EEG power features associated with reduced gaze towards social stimuli in autistic children, 2) analyze the relationship between these EEG markers and...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will provide $195,000 to the Research Institute at Nationwide Children's Hospital (RINCH) to conduct research characterizing the role of sleep brain dynamics in the emergence of depression in adolescents. Specifically, the study aims to: (1) identify the space-time profiles of sleep slow oscillations and spindles, and contrast-compare these properties...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), provides $134,730 to develop EEG biomarkers (EDbs) to predict the future risk of dementia and monitor cognitive decline in older adults. The project aims to leverage deep learning on existing datasets from over 8,000 older adults to construct EDbs using EEG measures across different sleep/wake stages. The...