Project Grant R21NS140563
- The University of Chicago received a $3.89 million Project Grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program. The grant will fund research from August 2022 through August 2025 to directly measure and manipulate the spiking activity of locus coeruleus and ventral tegmental area axons in the hippocampus of mice during hippocampal-dependent...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides $828,335 to the University of Chicago to investigate the roles of inhibitory and disinhibitory neural circuits in the formation, stabilization, and competition of neural assemblies in the cortex. The project aims to experimentally test theoretical...
- This federal Project Grant award of $481,126 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) is funding research by the University of Chicago to molecularly and functionally characterize how the UNC-6/netrin axon guidance cue system provides repulsive signals to growing neurons. The project aims to develop new biochemical strategies to study UNC-6-UNC-5 receptor complexes...
- This federal Project Grant award in the amount of $458,806.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will support research conducted by the University of Chicago to characterize the fundamental differences between projection and local pathways in proprioceptive signaling in Drosophila larvae. Key activities include using advanced...
- This federal Project Grant award of $183,751 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support research to develop a miniaturized ultra-widefield micro-camera array microscope (MCAM) capable of imaging a large area of the cerebellar cortex with cellular resolution in freely behaving mice. The goal is to enable recordings of cerebellar neuronal...
- This Project Grant award of $148,040, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate how the cerebellar circuit's synaptic properties may underlie precisely timed behavioral outputs. The research project, led by the University of Colorado-Denver, will leverage optical tools to measure mossy fiber and granule cell...
- This federal Project Grant award of $298,805 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research at Duke University to investigate the role of specific inhibitory and disinhibitory circuits within the cerebellum in learning and behavior. The research aims to establish a better understanding of how inhibitory interneurons, particularly molecular...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services, awarded a $4,528,840 Project Grant to The Salk Institute For Biological Studies under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The three-year award beginning August 19, 2022 will fund research to functionally dissect cerebellar output circuits that orchestrate limb motor control. Specifically, the grantee will...
- The University of Chicago was awarded a $625,000 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences CFDA program. This three-year collaborative research project will elucidate the molecular mechanisms underlying the activation of ROBO receptor proteins that guide the growth and navigation of axons during neural circuit development. The research aims to determine how ROBO receptors have evolved to allow for the...
- This federal Project Grant award of $1,208,677.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research conducted by President and Fellows of Harvard College, doing business as Harvard Medical School, over an 8-year period from August 2025 to July 2033. The primary goal of this research is to answer the question: How do the...
The University of Chicago received a $433,592 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award will fund research to assess the conditions under which long-term depression (LTD) is evoked in the cerebellum of intact mice. Specifically, the researchers will investigate how ramping activity in granule cell and Purkinje cell neurons impacts LTD, a key form of synaptic plasticity that may underlie motor adaptation and learning. The project aims to provide novel insights into the physiological mechanisms governing cerebellar plasticity under more realistic, in vivo recording conditions compared to prior slice-based studies. The award period runs from August 1, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $433.6k | 7/29/25 |