This federal Project Grant award for $504,888, provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), supports the development of an engineered biomaterial to improve the survival and integration of human induced pluripotent stem cell-derived neurons (hiPSC-neurons) transplanted for the treatment of spinal cord injury. Specifically, the project aims to optimize a growth factor-release system within an injectable hydrogel to enhance the long-term survival of hiPSC-neurons when transplanted, thereby improving anatomical and functional outcomes in a preclinical model of cervical spinal cord injury. This research leverages the awardee's, The Leland Stanford Junior University, expertise in biomaterials, stem cell biology, and translational bioengineering. The award period runs from June 14, 2024 to April 30, 2027.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $168.3k | 4/16/25 | ||
| Not listed | $168.3k | 6/14/24 | ||
| Not listed | $168.3k | 6/14/24 |