This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders federal grant program (CFDA 93.853), will provide $123,616.00 to investigate the role of the blood-brain barrier in the trafficking of prenatal liver-derived immune cells into the brain. The research aims to elucidate the cellular and molecular development of the blood-brain barrier and its impact on cellular...
This federal Project Grant award of $985,026 from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders, aims to investigate the roles and mechanisms of epitranscriptomic regulation in the development and function of the mammalian nervous system, as well as the pathological consequences of disrupting these processes. The research program will utilize mouse models and human induced...
The University of California, San Diego (UCSD) was awarded a $434,500 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The funding will support research to investigate the regulation of Schwann cell mitochondria homeostasis and its role in painful peripheral neuropathy. Specifically, the project aims to examine how the low-density lipoprotein...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the federal Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to establish the feasibility of cell-type specific modulation of the blood-brain barrier (BBB) using a novel "MagnetoBBB" approach. The total award amount is $447,501.00 with a project period from September 1, 2024 to August 31, 2026. The key objectives are to: 1)...
This Project Grant award of $597,999.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will fund research focused on understanding the neuronal populations and central sensitization mechanisms that underlie mechanical allodynia, a condition where normally innocuous touch or movement becomes painful after an injury. The research...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on advancing research to correct pathophysiological myelin formation in hereditary neuropathies. The $352,073 award to the Board of Regents of the Nevada System of Higher Education, operating through the University of Nevada, Reno, will support rigorous in vivo testing of...
This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,341,874 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF). The grant supports research focused on elucidating the molecular mechanisms that control dendrite development, as well as studying mechanosensation and regeneration in Drosophila dendritic arborization (DA) neurons. Key...
This $210,600 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund research to investigate how Wnt signaling mediates the formation of repair cells from Schwann cells in the peripheral nervous system. The primary goals are to 1) provide functional tests of the role of Wnt receptors and ligands in controlling repair cell...
This federal Project Grant award of $801,329 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research at the University of Illinois to investigate the role of Wnt/beta-catenin signaling in maintaining blood-brain barrier integrity and its potential to reverse neurological disorders associated with SARS-CoV-2 infection. The 5-year project aims to determine...