This Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) provides $713,277 to Boston University Medical Campus to conduct research on the translational impact of genetic susceptibility to complex toxic exposures on blood-brain barrier function and age-related neurological outcomes in Gulf War Illness. The award will support the project from September 1, 2024 through August 31, 2027. As part of this...
This $6,214,900 Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program supports research on the role of genetic risk factors and immune response on neurovascular unit (NVU) function in post-traumatic brain injury (TBI) cognitive impairment. The primary awardee, the Scintillon Institute, a non-profit biomedical research organization in San Diego, California, will conduct this advanced scientific investigation over...
This $300,387 Project Grant award, funded by the Department of the Army Medical Command under the Military Medical Research and Development (CFDA 12.420) program, supports an "Integrated Precision Immunology Approach for Developing an Fc-Fusion Vaccine to Treat Frontotemporal Dementia" at Twilight Bioscience, Inc. in Topsfield, MA. The 2-year award period runs from February 1, 2025 to January 31, 2027 and aims to advance biomedical research initiatives focused on transforming...
This federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $299,937.00 to The Feinstein Institutes For Medical Research to conduct research on visualizing neural synaptic density in systemic lupus erythematosus (SLE) to better understand mechanisms of brain dysfunction. The award period runs from July 15, 2024 to July 14, 2026. The Feinstein Institutes, a non-profit research organization, will utilize this...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA 93.853 "Extramural Research Programs in the Neurosciences and Neurological Disorders", provides $596,570.00 to Vanderbilt University for a research project aimed at improving the sensitivity and specificity of diffusion MRI (dMRI) techniques. The key objectives are to: 1) develop and validate improved methods for sub-voxel fiber identification and tissue...
This $1,127,000 federal Project Grant award from the National Institutes of Health (NIH) Office of the Director's Trans-NIH Research Support program (CFDA 93.310) will fund a transformative research program at Duke University to map and dissect the brainstem neural circuits that coordinate orofacial rhythmic movements such as licking, breathing, and swallowing. The research aims to shed light on the neural mechanisms underlying these critical life functions and how they may be impacted in...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $300,892 to Duke University to conduct high-resolution diffusion imaging research on brain connectivity in healthy aging and Alzheimer's disease. The study aims to examine how white matter structural and functional connectivity, as measured by advanced diffusion-weighted imaging techniques, relate to cognitive performance and age-related differences in a sample of 140 healthy adults aged 18-80...
This federal Project Grant award, issued by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $4,693,249 to the University of California, Los Angeles (UCLA) to conduct research on defining the molecular spectrum of white matter vascular lesions that drive vascular cognitive impairment and dementia (VCID). The project aims to develop a better understanding of...
This Project Grant award of $2,163,115.00, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research conducted by Pathmaker Neurosystems Inc. to develop a noninvasive neuromodulation approach to slow the progression of amyotrophic lateral sclerosis (ALS) by suppressing neuronal hyperexcitability. The research, taking place in Boston, MA, aims to explore this innovative therapeutic method over the 2-year performance period...
The federal Project Grant award in the amount of $564,901.00, awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research to develop a drug delivery strategy using exosomes as nanocarriers to target the brainstem. This multi-year award, with a project period from September 1, 2024 to August 31, 2027, will be performed by the Mayo Clinic, a leading non-profit academic medical center. The research aims to explore innovative...