Project Grant R21MH144714
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded The Ohio State University a $10.1 million Project Grant (Drug Use and Addiction Research Programs, CFDA 93.279) on September 12, 2025, for the MODEL-PAIN research initiative. This prospective observational study of 2,400 emergency department patients will deliver comprehensive data-driven modeling to characterize acute pain phenotypes, identify optimal individualized pain treatment strategies, and...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Pittsburgh a Project Grant totaling $378,984 under the Mental Health Research Grants program (CFDA 93.242), with an award date of March 13, 2026 and completion date of February 28, 2031. This K23 mentored research grant supports a novel neurobiological investigation examining the relationship between peripheral inflammatory markers and reward-related neural circuitry dysfunction in adolescents...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Wisconsin–Madison a $822,352 Project Grant under the Mental Health Research Grants program (CFDA 93.242) on June 5, 2026, to support a mechanistic analysis of the transition from nonsuicidal self-injury (NSSI) to suicidal behavior in adolescents. Led by Principal Investigators Taylor Burke and Brooke Ammerman with Co-Investigators Richard Liu, Ross Jacobucci, and Thomas Serre, the research will...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Pittsburgh a $185,552 Project Grant effective September 19, 2025, under the Mental Health Research Grants program (CFDA 93.242) to investigate neurocognitive responses to social threat and their connection to suicidality in adolescent girls. The research will generate scientific knowledge through a K23 mentored research career development award examining how sustained neural responsivity to...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Illinois a Project Grant totaling $100,228 under the Mental Health Research Grants program (CFDA 93.242) to implement suicide prevention strategies in outpatient pediatric behavioral health settings. The project, which commenced on September 30, 2026, and concludes on May 31, 2028, will deliver qualitative research findings and contextually tailored implementation strategies designed to...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Miami a $731,258 Project Grant effective March 1, 2026, through November 30, 2030, under the Mental Health Research Grants program (CFDA 93.242). This research project addresses critical gaps in understanding the neural mechanisms underlying Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) by utilizing real-world, high-stakes events to map neural dynamics...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Pittsburgh a $728,751 Project Grant under the Mental Health Research Grants program (CFDA 93.242) for the period April 1, 2026 through March 31, 2031. This research project, titled "Dissecting Antidepressant Placebo Expectancy-Mood Dynamics," investigates the neural mechanisms underlying placebo effects in antidepressant treatment for major depressive disorder (MDD). The study will...
- Federal Grant Award Summary The Ohio State University received a $390,906 Project Grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396), effective April 1, 2026 through March 31, 2027. This research initiative, titled "Decoding Dural Nociceptors as Drivers of Immune Suppression in Glioblastoma," investigates the role of pain-sensing sensory neurons (nociceptors) in regulating the immunosuppressive tumor microenvironment...
- Federal Project Grant Award Summary Oregon Health & Science University (OHSU) received a $109,076 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on December 19, 2025, with a completion date of July 31, 2029. This research project, titled "Internalizing Symptoms in Adolescence: Understanding the Roles of Negative Life Events, Emotion Regulation, and the Brain Over Time," will generate...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $150,104 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded December 30, 2025, with a completion date of June 30, 2028. The grant supports basic neuroscience research investigating intracellular signaling mechanisms in the external globus pallidus (GPE), a critical hub nucleus within the basal ganglia involved in behavioral...
The National Institute of Mental Health (NIMH) awarded The Ohio State University a Project Grant totaling $433,125 under the Mental Health Research Grants program (CFDA 93.242) for the period July 1, 2026 through June 30, 2028. This R21 exploratory research grant supports an innovative investigation into the mechanisms linking chronic pain to suicide risk, addressing a critical public health gap affecting an underserved population. The study applies the Catastrophizing, Anxiety, Negative Urgency, and Expectancy (CANUE) model to examine how intolerance of uncertainty and anxiety sensitivity interact to amplify pain-related distress and momentary suicide risk. The primary deliverables include empirical research data generated from a multimodal study design enrolling 90 adults with chronic musculoskeletal pain and elevated suicide risk. Participants will complete comprehensive laboratory sessions incorporating validated self-report assessments, behavioral tasks, and quantitative sensory testing to evaluate pain sensitivity and affective responses, followed by a 21-day ecological momentary assessment phase. The research will produce novel findings regarding the cognitive-affective mechanisms underlying suicide vulnerability in chronic pain populations, contributing to the development of targeted, evidence-based suicide prevention strategies for this at-risk group and advancing the field's understanding of pain-related psychiatric comorbidities.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $433.1k | 6/19/26 |