This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $553,788 to Northwestern University to conduct research on the microcircuit mechanisms behind the distributed cortical contributions to working memory. The research aims to understand how genetically identified cell types in the primary visual cortex (V1) and premotor cortex (M2) of mice interact to generate different activity timescales...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 - Mental Health Research Grants will fund research to delineate the molecular programs in the thalamus that sustain synchronized thalamo-cortical neural activity underlying working memory. The $423,750 award to Rockefeller University, spanning August 1, 2024 to April 30, 2029, will focus on identifying the chronic transcriptional and gene-regulatory programs, as well as the acute activity-dependent...
This $2,286,510 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to develop a computational framework for understanding neural circuit dynamics and their role in cognition. The award to New York University will fund the development of analytical models, called Oscillatory Recurrent Gated Neural Integrator Circuits (ORGANICS), to simulate neural mechanisms underlying attention, working memory,...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is funding a research project titled "Neural Circuit Mechanisms in Observational Spatial Working Memory" at Baylor College of Medicine. The $504,453 award, effective from Sep 5, 2024 to Jul 31, 2029, will support research to study the behavioral and neural circuit processes underlying reward-directed observational learning. The project...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to identify the circuit mechanisms underlying interactions between distinct learning systems. The $1,425,651 award to the University of Maryland, Baltimore will be used to conduct large-scale behavioral experiments and high-density neural recordings to determine how the prefrontal cortex coordinates learning across procedural and...
This federal Project Grant award, valued at $242,310.00 and awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research on the role of reward mechanisms in episodic memory formation within the hippocampus. The project aims to investigate how reward expectation and delivery influence head scanning behavior and the potentiation of hippocampal place fields, which are important for spatial and episodic memory. Through...
This $2,306,736 federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to reveal critical neural mechanisms for intelligent reward-driven learning and decision-making. The primary focus is on investigating how the hippocampus generates "non-local" neural representations that may be used for evaluating options (theta sequences) and updating reward values (sharp-wave-ripple events) during...
This $495,907 federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants will fund research at Florida State University to investigate the neurobiological basis of spatial memory and action coordination. The project aims to determine how the hippocampus, anterior thalamus, and parietal cortex function as a circuit to transform allocentric (map-like) spatial representations into egocentric (body-centered) actions during...
This $126,619 federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to understand the neural dynamics underlying spatial reward memory in the brain. The award to The Leland Stanford Junior University is for a project that combines advanced neural recording technologies and innovative behavioral tasks in rodents to investigate how the hippocampus and medial entorhinal cortex encode and...
The federal Project Grant award R01MH136355 for $571,694.00 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The award supports research to elucidate the circuit mechanisms underlying spatial and non-spatial learning in the entorhinal-hippocampal network of rats. Key activities include simultaneous neural recordings across CA1-2, medial entorhinal cortex (MEC), and lateral entorhinal cortex (LEC) to examine how area and...