Project Grant R21MH134530
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant totaling $771,272 to New York University School of Medicine, with an award date of March 15, 2026, and ultimate completion date of December 31, 2030, under the Mental Health Research Grants program (CFDA 93.242). This research project investigates prenatal maternal brain plasticity and its associations with maternal and infant neurobehavioral health, with a specific focus on understanding how...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Virginia a $768,909 Project Grant under the Mental Health Research Grants program (CFDA 93.242) effective May 1, 2025, through January 31, 2030. This research initiative, titled "Synchronous Network Activity in the Maturing Prefrontal Cortex: Mechanistic Impact of Birth Timing and Serotonin," investigates how premature birth affects brain development and cognitive function. The...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $200,376.00 under the Mental Health Research Grants program (CFDA 93.242) to The Regents of the University of California, San Francisco for research activities spanning April 1, 2026, through March 31, 2031. The grant funds a longitudinal research investigation examining the mechanisms through which prenatal maternal inflammation (PMI) and parenting behaviors influence child mental health...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $394,200 to the Research Foundation For Mental Hygiene, Inc. (RFMH) under the Mental Health Research Grants program (CFDA 93.242) beginning August 1, 2025, with a completion date of July 31, 2030. This project grant funds a five-year clinical research investigation examining the role of the anterior hippocampus in the pathogenesis of major depressive disorder (MDD). The research leverages functional magnetic...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Feinstein Institutes for Medical Research a Project Grant of $519,558 under the Mental Health Research Grants program (CFDA 93.242), effective June 15, 2025 through April 30, 2030. The research project focuses on identifying and validating cerebellar-cortical circuitry biomarkers as predictive indicators of antipsychotic treatment response in first-episode psychosis patients. The primary deliverables...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded $717,688 to Icahn School of Medicine at Mount Sinai under the Mental Health Research Grants program (CFDA 93.242) on May 1, 2026, for a four-year project period concluding April 30, 2030. This K01 Career Development Award supports a research investigation into the molecular and epigenetic mechanisms by which postpartum stress interacts with parity to influence vulnerability to perinatal and postpartum mood...
- Federal Project Grant Award Summary Yale University received a $838,378 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective March 10, 2026, with a completion date of February 28, 2031. The award supports a five-year neuroscience research project investigating the neural mechanisms underlying infant social behaviors and parent-infant interactions. The research focuses on somatostatin-expressing neurons in...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded $359,433 to the Seattle Institute For Biomedical And Clinical Research under the Mental Health Research Grants program (CFDA 93.242) on September 24, 2025, with a completion date of September 23, 2027. This project grant funds basic neuroscience research investigating the role of the FKBP5 gene in serotonergic function and fear response regulation. The research will develop and utilize novel molecular...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a Project Grant of $778,548 to the Research Foundation For Mental Hygiene, Inc. (Nathan S Kline Institute for Psychiatric Research) on September 19, 2025, under the Mental Health Research Grants program (CFDA 93.242). This five-year research initiative, concluding July 31, 2030, investigates the neural mechanisms underlying social cognitive deficits in schizophrenia, with particular focus on the third visual...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded Child Mind Institute Inc. a $578,500 Mental Health Research Grants (CFDA 93.242) Project Grant effective May 1, 2025, through February 29, 2028. The award supports the development of integrated computational tools designed to link brain microstructure with functional dynamics in human and non-human primates. The project delivers three primary products: (1) an extension of the BrainBuilder tool to...
The National Institute of Mental Health (NIMH) awarded $467,368 to the Research Foundation For Mental Hygiene, Inc. (operating as the New York State Psychiatric Institute) on April 1, 2026, under the Mental Health Research Grants program (CFDA 93.242). This exploratory/developmental R21 project grant, extending through March 31, 2028, supports research investigating the relationship between gestational serotonin levels and offspring neurodevelopment. The research leverages an existing longitudinal study of 375 mother-infant dyads to examine whether maternal whole blood serotonin in early pregnancy (14-18 weeks) correlates with changes in placental gene expression, cord blood serotonin levels, infant thalamocortical connectivity, and subsequent cognitive and behavioral outcomes through 30-36 months of age. The study builds upon prior animal research demonstrating that maternal serotonin functions as a critical growth factor during fetal brain development. The project utilizes existing biological specimens and neuroimaging data collected under a parent R01 grant (R01MH119510), eliminating the need for new data collection and enabling cost-effective hypothesis testing. Deliverables include analysis of maternal and cord blood serotonin measurements, placental transcriptome evaluation, structural connectivity measures from infant neuroimaging conducted at 2-4 weeks of age, and prospective cognitive and behavioral assessments. This research addresses critical limitations in prior human studies by examining conserved pathways identified in animal models within a prospective, community-based cohort rather than a restricted clinical population, thereby advancing understanding of how prenatal maternal physiology influences early child neurodevelopment.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $467.4k | 3/16/26 |