Project Grant R21HD115568

Award Date 4/1/25
Completion Date 3/31/27
Dollars Obligated $233K
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Missouri, USA

This Project Grant award of $233,250 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund a research study on the mechanisms underlying endometriosis pain and changes in pain after surgical treatment.

The study will be conducted by The Washington University, a prominent private research institution, over a two-year period from April 1, 2025 to March 31, 2027. The research aims to identify the central and peripheral factors, including estrogen levels and estrogen receptor expression, that contribute to endometriosis pain. It will also examine how these factors relate to pain reduction after surgical removal of endometriosis lesions. The findings could lead to improved treatment approaches for endometriosis pain through the development of new or repurposed pain therapies and personalized prediction models for surgical outcomes.

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