The National Institute of Child Health and Human Development (NICHD) awarded a $161,000 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Research Foundation for the State University of New York (RF SUNY). The grant, awarded on July 23, 2024, will support research to identify the hepatic epigenomic adaptations to excessive early-life cholesterol exposure due to maternal hypercholesterolemia, and evaluate the efficacy of maternal...
The National Institute of Child Health and Human Development (NICHD) awarded a $171,728 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Weill Medical College of Cornell University to study the role of premature infant gut microbiome dysbiosis in mediating immune development and response to respiratory syncytial virus (RSV) infection. The research aims to define how the altered gut microbiome in premature infants impacts their ability to mount effective...
The National Institute of Child Health and Human Development (NICHD) awarded a $451,000 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Regents of the University of California, San Francisco (UCSF) to investigate the therapeutic potential of maternal breast milk components for preterm white matter injury (WMI). The key objectives are to: 1) Perform high-throughput screening of breast milk components to identify pro-myelinating compounds, and 2) Test...
This Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a comparative study investigating the mechanistic effects of human milk feeding on neurodevelopment in preterm infants. The $239,399 award to the Regents of the University of Idaho will utilize a neonatal piglet model to examine how human milk feeding influences intestinal barrier function,...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research into the neurobiological mechanisms underlying maternal behavior in mice. The $1,572,111 award to Baylor College of Medicine aims to elucidate the role of the TRPC5 ion channel in regulating maternal behaviors, such as pup retrieval and nursing, and to assess whether...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $1,034,229 to Albert Einstein College of Medicine to conduct research on the neural circuits and mechanisms underlying infant-directed behavior in both males and females. The key objectives of this 5-year grant are to: 1) determine how circuit activity in molecularly defined neuronal...
The National Institute of Child Health and Human Development (NICHD) awarded a $154,796 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Massachusetts Institute of Technology (MIT) to develop a biomimetic, 3D mammary lobe model that can faithfully mirror breast milk synthesis processes and serve as a screening testbed for evaluating the safety of drugs and therapeutics during lactation. The project aims to understand how...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $246,390 to Cornell University to conduct research on the molecular mechanisms regulating human milk production and composition. The research aims to elucidate physiological factors contributing to insufficient human milk production, a prevalent issue that leads to...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 Child Health and Human Development Extramural Research, aims to identify the molecular mechanisms linking lactation to metabolism. The $751,710.10 award, granted on August 15, 2024, will fund investigations to understand the effect of maternal gestational diabetes on mammary epithelial cell (MEC) progenitor insulin signaling and MEC profiles, as...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), will provide $309,496 to Duke University over a 2-year period ending June 19, 2027. The project aims to elucidate the mechanisms by which key transcription factors (MAFB, CMAF, and BLIMP1) regulate neonatal intestinal nutrient absorption and immune development. Through genetic...