This $159,362 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to characterize how breast milk IgA shapes the development of the preterm infant gut microbiome and promotes resistance to pathobionts. The primary goals are to: 1) Determine if maternal IgA binding restricts colonization of Enterobacteriaceae and promotes the establishment of obligate anaerobes...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 Child Health and Human Development Extramural Research, aims to define the role of premature infant gut microbial dysbiosis in mediating immune development and response to respiratory syncytial virus (RSV) infection. The $171,728 award to Weill Medical College of Cornell University will support research to investigate how the altered gut microbiome in premature infants...
This federal Project Grant award, funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the impact of the gut microbiota of undernourished mothers with environmental enteric dysfunction on vascular remodeling at the fetal-placental interface. The $104,066 award, granted to The Washington University in St. Louis, aims to characterize the effects of...
This $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund a study to create a novel patient selection framework for early life interventions targeting infection, inflammation, and growth outcomes in very preterm infants. The study aims to leverage a registry of over 3,600 very preterm infants and their mothers to develop perinatal phenotypes that...
This Project Grant from the National Science Foundation Division of Behavioral and Cognitive Sciences provides $255,134 to support research titled "Collaborative Research: Biocultural Context Linking the Gut Microbiome, Iron, and Reproduction." The award is made under the Social, Behavioral, and Economic Sciences program (CFDA 47.075), which aims to promote basic research in these fields. Specifically, the grant will fund a longitudinal study from September 2022 through August 2026...
This Project Grant award of $689,409 from the National Institute of Child Health and Human Development (NICHD) under CFDA Program 93.865 - Child Health and Human Development Extramural Research will support a clinical translational study to determine the role of the microbiota-gut-brain axis (MGBA) in perinatal depression (PND). The 5-year study will recruit 158 racially diverse pregnant women to investigate how interactions between maternal and microbial systems influence depressive symptom...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate the impact of influenza A virus (IAV) infection on the maternal gut microbiome and its effects on fetal and perinatal outcomes. The $149,528 award, with a project period from May 7, 2025 to Nov 30, 2027, will be conducted by The Johns Hopkins University to...
This federal Project Grant award for $498,000.00, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support a longitudinal study to identify interactions between viruses, bacterial microbiota, and cellular responses to vaccination in HIV-exposed uninfected (IHEU) and HIV-unexposed (IHU) infants. The key objectives are to: 1) Integrate viral metagenome data with bacterial...
The National Institute of Child Health and Human Development (NICHD) awarded a $415,832 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the University of Nebraska Medical Center to investigate the mechanisms by which severe anemia and red blood cell transfusions induce and exacerbate brain inflammation in anemic murine neonates, which can lead to long-term neurodevelopmental impairment. The research project will: 1) elucidate how anemia and transfusions...
This Project Grant award, totaling $854,736, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant aims to develop robust statistical methods for analyzing longitudinal microbiome studies, which are important for understanding the forces that shape the human microbiome and enabling the development of microbiota-based interventions. Specifically, the grant will fund the development of new...