This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), with CFDA program title "Child Health and Human Development Extramural Research", provides $186,250 to Syracuse University to conduct research on the molecular mechanisms regulating primordial follicle formation in the mouse ovary. The research aims to elucidate the role of insulin signaling in primordial follicle assembly and examine primordial follicle formation in a mouse model of gestational diabetes. The award period runs from July 15, 2024 to June 30, 2026. The research will utilize techniques including immunohistochemistry, confocal microscopy, ovary organ culture, and genetics to enhance understanding of the mechanisms involved in establishing the primordial follicle pool, with the goal of improving research and treatment of female infertility conditions.
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