Project Grant R21GM160845
- The University of Tennessee was awarded a $265,343 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to fund the "Picturing Possibilities and Envisioning Selves (PIPES3)" project. The project aims to increase the number of rural Appalachian high school students pursuing post-secondary education and entering STEMM (Science, Technology, Engineering, Math, Medical) fields. The...
- This $299,396 National Science Foundation project grant supports research into the role of lipids in modulating synaptic plasticity of ion channels. Funded under the Biological Sciences program (CFDA 47.074), the two-year award to the University of Tennessee will elucidate the microscopic mechanisms involved in ion transport across membrane-associated protein channels. Researchers will focus on dynamic and structural features of biological membranes and leverage non-invasive scattering...
- The University of Tennessee received a $600,000 Project Grant award from the National Science Foundation Division of Integrative Organismal Systems. The grant falls under the Biological Sciences program (CFDA 47.074) and will support collaborative research titled "COLLABORATIVE RESEARCH: EDGE FGT: FUNCTIONAL GENOMIC TOOLS FOR PARASITIC NEMATODES AND THEIR BACTERIAL SYMBIONTS" from August 2021 through July 2025. The research aims to develop functional genomic tools to study parasitic...
- This Project Grant award of $793,500 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will fund research at the University of Tennessee at Chattanooga (UTC) to investigate changes in bacterial cell membrane dynamics due to polyunsaturated fatty acid (PUFA) modifications. The key objectives are to: 1) Interrogate the nature and degree of PUFA incorporation into membrane phospholipids of Vibrio cholerae, and 2)...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $335,578 to the University of Tennessee to conduct research on the chemical and biological roles of five-carbon (C5) metabolism. The key objectives are to: (1) create new cell-permeable C5 analogs and develop inhibitors/tools targeting isopentenyl pyrophosphate isomerase (IPPI) activity; (2) develop a high-throughput assay...
- The National Science Foundation awarded a $752,674 Project Grant to the University of Tennessee under the Mathematical and Physical Sciences program (CFDA 47.049) from July 1, 2021 to June 30, 2024. The grant funds research to create bio-based peptides and determine their mechanisms as ice recrystallization inhibitors. The Mathematical and Physical Sciences program aims to advance scientific knowledge and understanding in core disciplines, consistent with the scope of this research. The...
- This three-year, $1,368,422 project grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports the development of cryogenic electron microscopy (cryo-EM) to study phase separation in lipid membranes. Frederick A. Heberle of the University of Tennessee and M. Neal Waxham of the University of Texas Health Science Center at Houston will optimize cryo-EM imaging techniques to visualize nanoscale lipid raft domains in cell membranes. Goals include...
- This federal Project Grant award of $416,240 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The purpose of the award is to support the University of Maryland, Baltimore's "Training Program in Cellular and Molecular Membrane Biology." The program provides interdisciplinary research training at the molecular, cellular, and systems biology interface, with a focus on understanding the...
- This $395,455 Project Grant was awarded on August 1, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The goal of the project is to develop and apply computational methods for biomolecular structural modeling using cryo-electron microscopy (cryo-EM) data. Key products and services to be delivered include: Expanding and enhancing the capabilities of structure modeling methods to improve accuracy and...
- This $1,444,500 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) aims to develop new cryogenic electron microscopy (cryo-EM) methods to visualize the structural heterogeneity of ribosomes at the single-molecule level in cells. The award, effective September 2, 2024 through August 31, 2027, will enable the principal investigator to pursue strategies to extend a novel technique called 2D template...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $436,547.00 to the University of Tennessee for the development of a model to determine fluid bilayer structure from cryo-EM images of biomembranes. The project, with a performance period from September 1, 2025 to August 31, 2027, aims to advance scientific understanding of biological processes through innovative research approaches in molecular biology, genetics, and cellular science. As a prominent public land-grant research university, the University of Tennessee has a demonstrated track record of executing complex research projects across diverse scientific and technological domains to support federal agencies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $436.5k | 8/13/25 |