The federal Project Grant award R21EY036170 is funded by the National Eye Institute (NEI) under the Vision Research (CFDA 93.867) program. The $245,243 award supports research to develop and validate a novel method for measuring ocular pulse amplitude (OPA) using applanation-based tonometry. The project aims to 1) validate the OPA measurement technique on non-human primates with implanted intraocular pressure (IOP) telemetry systems, and 2) assess the repeatability and reproducibility of the OPA measurements in normotensive and hypertensive eyes. This research is intended to improve the reliability and accuracy of tonometry, which is critical for understanding the role of OPA in normal and abnormal ocular physiology. The project will be conducted by the Office of Research Administration Division at Duke University over a 2-year period from March 2025 to February 2027.
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