Project Grant R21EB038597
- The National Institute of Child Health and Human Development awarded the University of Washington $383,200 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to optimize transcutaneous spinal cord stimulation intensity for gait training in children with cerebral palsy. The research systematically evaluates how varying spinal stimulation intensities affect gait biomechanics in ambulatory children with bilateral cerebral palsy. In the first aim,...
- Federal Grant Award Summary The University of Washington, Seattle, WA received a $427,625 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective May 21, 2025, with a completion date of April 30, 2027. The research project investigates whether electrical stimulation (ES) enhances the therapeutic capacity of neural stem cell (NSC) transplants...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $150,342 to the University of Washington on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of how long-term, closed-loop, epidural spinal cord stimulation affects neuropathic pain symptoms in rats with cervical spinal cord injury. The...
- The National Institute of Child Health and Human Development awarded the University of Washington $616,250 on September 1, 2026, through the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a randomized controlled trial evaluating non-invasive spinal cord stimulation combined with intensive treadmill training to reduce spasticity and improve mobility in children with cerebral palsy. The research will enroll children with cerebral palsy in a 24-session...
- The National Institute of Neurological Disorders and Stroke (part of the Department of Health and Human Services National Institutes of Health) awarded Oregon Health & Science University $5.363 million on August 18, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to optimize spinal cord stimulation parameters for pain and itch management. The research investigates how epidural spinal cord stimulation engages dorsal horn circuits, specifically targeting neuropeptide Y...
- The National Institute of Neurological Disorders and Stroke (part of the Department of Health and Human Services National Institutes of Health) awarded $367,075 to the University of Newcastle Upon Tyne on September 5, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Project Grant R01NS150256). The award funds research into paired stimulation plasticity for motor recovery following cervical spinal cord injury, with the goal of...
- The National Institute of Neurological Disorders and Stroke awarded Washington University in St. Louis $493,332 on August 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop a surface electroneurography device for in-office assessment of peripheral nerve recovery. Washington University partnered with Biocircuit Technologies to design a diagnostic system addressing limitations in current peripheral nerve injury...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,976 to Ecate LLC aims to develop a novel intraspinal stimulator system to restore sensation and volitional motor control in spinal cord injury patients. The project will fabricate nanopatterned stimulating electrodes coupled with custom CMOS chips to deliver spatially selective electrical stimulation to the spinal cord. This closed-loop neural interface system is intended...
- The National Institute of Neurological Disorders and Stroke awarded a cooperative agreement to Case Western Reserve University for $1,202,540 on September 1, 2026, to conduct an exploratory trial of the RESTORES (Revolutionary Electrical Stimulation Technology to Optimize Recovery of Everyone with Spinal Cord Injury) system. The recipient will customize and program open-source Networked Neuroprosthesis (NNP) components—a modular peripheral neurostimulation device designed to address multiple...
- The National Institute of Neurological Disorders and Stroke awarded Drexel University $149,190 on July 14, 2026, under CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) to conduct research on transcutaneous spinal cord stimulation and its mechanisms for reducing spasticity following spinal cord injury. The research investigates whether transcutaneous spinal cord stimulation improves spasticity after spinal cord injury by upregulating KCC2, a chloride...
The National Institute of Biomedical Imaging and Bioengineering awarded the University of Washington $212,265 on August 21, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a closed-loop system for personalizing transcutaneous spinal stimulation (TSCS) amplitude during locomotor rehabilitation for individuals with neurological impairments from spinal cord injury, stroke, multiple sclerosis, traumatic brain injury, Parkinson's disease, and cerebral palsy. The research addresses the limitation that current TSCS parameter tuning relies on manual, subjective trial-and-error adjustment by trained clinicians, with stimulation amplitude held static throughout each session despite dynamic physiological changes. The project will collect experimental data to establish neuromechanical benchmarks using wearable sensors, enabling real-time personalization of TSCS parameters to maximize neuroplastic treatment effects and promote functional recovery. Work is performed in Seattle, Washington, with a period of performance through July 31, 2029. The award is classified as a Project Grant under the NIH R21 mechanism, supporting hypothesis-driven technology development for biomedical applications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $212.3k | 8/20/26 |