Project Grant R21EB038490
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the Regents of the University of Minnesota a $531,021 Project Grant on April 10, 2026, under CFDA 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health) to develop advanced radiofrequency (RF) and gradient technologies for whole-brain functional and structural connectivity mapping at 10.5 Tesla (10.5T) magnetic resonance imaging (MRI). The...
- The Regents of the University of Minnesota received a $599,994.30 Project Grant award from the National Institutes of Health National Institute of Biomedical Imaging and Bioengineering to develop novel radiofrequency hardware for use at 10.5 Tesla to obtain functional magnetic resonance imaging signals at ultra-high resolutions in non-human primates. The goal is to directly test how well whole brain directional connectivity estimates from fMRI correspond with ground truth tract tracing...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded $471,967 to the Regents of the University of Minnesota on May 1, 2026, with completion targeted for February 28, 2030. This Project Grant supports the development of dual density-dependent molecular AND gate binders—engineered bispecific targeting ligands designed to...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the University of Wisconsin-Madison a Project Grant totaling $2,375,411 under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award, effective August 1, 2025, with completion targeted for May 31, 2029, supports the design and development of magnetic resonance imaging (MRI) technologies intended to enhance clinical value...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the Regents of the University of Minnesota a Project Grant of $654,117 under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) on April 1, 2026, with completion scheduled for March 31, 2030. The University of Minnesota will conduct mixed-methods research to identify barriers and mitigation strategies for artificial intelligence...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded University of California, Berkeley a $1.28 million Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) effective July 1, 2025, with completion targeted for May 31, 2029. This award funds research and development of digital programmable radiofrequency (RF) coils designed to advance ultra-high-field (7 Tesla)...
- Federal Project Grant Award Summary The University of Michigan, through its Office of Research and Sponsored Projects, received a Project Grant award of $149,264 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award, effective March 26, 2026, with a completion date of November 30, 2027, supports the development of advanced Magnetic Resonance...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering awarded The Johns Hopkins University a $477,360 Project Grant on August 14, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to enhance the robustness and accessibility of open-source, vendor-neutral magnetic resonance imaging (MRI) technology through the Pypulseq platform. The project, concluding July 31, 2027, delivers three...
- Federal Project Grant Award Summary Objective Biotechnology, Inc., a Minneapolis-based minority-owned biotechnology firm, received a $416,925 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on September 15, 2025, with an ultimate completion date of August 31, 2027. The grant supports the development and commercialization of the mini-mscope, a miniaturized imaging device designed for mesoscale...
- Federal Grant Award Summary The University of Minnesota received a $1.31 million Project Grant (DP2 mechanism) awarded September 30, 2025, under the Trans-NIH Research Support program (CFDA 93.310) from the National Institutes of Health (NIH) Office of the Director. This award supports a three-year research initiative (through August 31, 2028) investigating neuroplasticity and cerebral blood flow as key resilience mechanisms in fast-moving superagers—older adults aged 75 and above who maintain...
The University of Minnesota received a $209,940 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective June 1, 2026 through May 31, 2029. The award supports the development of a portable phase-only parallel transmission (PPTX) interface designed to optimize radiofrequency (RF) transmit fields for phosphorus-31 magnetic resonance spectroscopy imaging (31P MRSI) at 7 Tesla. The PPTX interface will enable continuous adjustment of RF phase across multiple transmit channels and B1+ phase shimming to improve flip angle uniformity and signal-to-noise ratio across whole-brain imaging, addressing limitations inherent in conventional 8-channel 31P transceiver array coils. The primary deliverable is a digital-controlled, RF broadband, and portable interface system compatible with existing MRI scanners (1.5T, 3T, and 7T) that lack built-in parallel transmission capabilities. Upon completion, the technology will enable quantification of key brain metabolic markers including inorganic phosphate (PI), phosphocreatine (PCR), adenosine triphosphate (ATP), and nicotinamide adenine dinucleotide (NAD) concentrations, as well as intracellular pH values throughout the brain. This development addresses an unmet need for non-invasive whole-brain metabolic neuroimaging tools capable of detecting abnormal energy metabolism and impaired mitochondrial function in early-stage Alzheimer's disease and brain tumors.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $209.9k | 6/1/26 |