Project Grant R21DE034146
Award Date
8/1/24
Completion Date
7/31/26
Dollars Obligated
$197K
Federal Agency
National Institute of Dental and Craniofacial Research
Federal Grant Program
93.121
Assistance Type
Project Grant
Place of Performance
Los Angeles, CA 90095, USA
Similar Awards
This federal Project Grant award for $480,840, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to investigate the role of the Iroquois homeobox 1 (IRX1) gene in regulating oral tissue repair and maintenance. The research aims to determine the expression pattern of IRX1 during embryogenesis and homeostasis, identify the role of IRX1 in oral tissues using lineage tracing models,...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,029,497 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Oridivus LLC located in Decatur, Georgia. The purpose of this grant is to compare the efficacy of FTY720 nanofibers versus platelet-rich plasma (PRP) in improving oral wound healing in rodent and porcine animal models. The goal is to develop an immunoregenerative approach to enhance oral wound healing, which is a significant...
This Project Grant award from the National Institute of Dental and Craniofacial Research (CFDA 93.121, Oral Diseases and Disorders Research) provides $158,500.00 to the Trustees of Indiana University, doing business as Indiana University Indianapolis, to conduct research on how diabetes affects oral epithelial stem cells and wound healing. The key objectives are to determine how diabetes disrupts the oral epithelial stem cell microenvironment and impairs stem cell function, leading to...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $432,209 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the University of California, Los Angeles (UCLA) for a 2-year period starting on August 1, 2023. The funding supports research to investigate the role of the CXCL10-CXCR3 axis in the compounding effects of diabetes mellitus on periodontitis. Specifically, the research aims to further elucidate the role of CXCL10 in the...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $180,943.00 to the University of California, Los Angeles (UCLA) to investigate the therapeutic targeting of apical periodontal T-cells in chronic oral inflammation. The key products and services to be delivered include: Establishing the physiological role of the calcium signaling protein ORAI1 in apical periodontitis, a...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121), provides $808,264 to The Medical University of South Carolina to conduct research on the mechanisms of filopodia-mediated intracellular delivery of small interfering RNAs (siRNAs) via peptide carriers. The goal is to elucidate the mechanisms underlying filopodia-directed cell entry of the RD3AD-siRNA complex in...
This $249,000 Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121) will fund research to elucidate the mechanism of action and impact of radical-S-adenosylmethionine ribosomally synthesized and post-translationally modified peptides (RAS-RIPPs) produced by oral Streptococcus bacteria on the human oral microbiome. The primary goals are to define the mechanism of action of...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $608,632.33 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Research Foundation For The State University Of New York (RF SUNY). The award, effective September 1, 2024, supports a research project investigating the role of rare chemosensory epithelial cells known as "tuft cells" in salivary gland immunity. The project aims to utilize advanced microscopic techniques,...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $111,701.00 to the University of Illinois at Chicago to conduct research on the mechanism and impact of Streptococcal RAS-RIPPS on the human oral microbiome. The award period runs from August 1, 2023 to July 31, 2025. The key objectives of this research project are to elucidate the mechanism of action of the RAS-RIPP...
This Project Grant award of $155,500 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will support a comprehensive examination of the oral virome and its interactions with the oral microbiome. The research aims to shed light on the role of viruses in maintaining oral health and contributing to disease, with the goal of illuminating a neglected aspect of the oral microenvironment and potentially...