Project Grant R21DE034090
- This Project Grant, awarded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), supports research to develop a novel 3D-printed mineral framework and cryogel scaffold to improve bone regeneration in head and neck cancer patients suffering from radiation-induced osteoradionecrosis. The $533,675 grant, with a performance period from July 1, 2025 to March 31, 2030, aims to test the central...
- The Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), provides $306,633 to Ther-Ai LLC to develop CRANIAMAP, a foundational software module that enhances auto-segmentation and landmarking capabilities for cone beam computed tomography (CBCT) scans. This SBIR Phase I project aims to outperform existing AI-based tools, achieving at least 90% accuracy in segmenting critical...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $350,000 project grant to Deep Reasoning AI Inc. The grant will support the development of the Deep Reasoning AI Virtual Anatomical Technology & Augmented Reasoning (DR-AIVATAR) platform, a multi-agent AI system for high-precision, personalized 3D anatomical modeling, surgical planning, and decision-making. The initial focus will be...
- This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $113,727 to develop new geometric deep learning methods for the automated, real-time evaluation of head shapes using 3D photogrammetry. The goal is to create quantitative models to assess the normalization of head shape after corrective surgery for craniosynostosis, a condition characterized by the premature...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,465,026 Project Grant on April 8, 2025 under the Oral Diseases and Disorders Research program (CFDA 93.121) to The University of Texas M.D. Anderson Cancer Center. The grant, titled "Harvard MD Anderson Collaborative to Reduce Lymphatic Morbidity in Head and Neck Cancer with Artificial Intelligence (HARMONIC-AI)," aims to leverage computational imaging and AI to enhance the detection and management of...
- This federal Project Grant award of $249,000.00, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), supports research to develop a novel patient-derived tumor organoid (tumoroid) platform for precision treatment of head and neck squamous cell carcinomas (HNSCCS). The key products and services to be delivered include: Establishing a high-throughput automated HNSCC tumoroid platform to capture tumor...
- This federal Project Grant award of $3,742,682 was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) to the Dana-Farber Cancer Institute, Inc. (DFCI) in Massachusetts. The grant supports research to dissect the role of the chemokine CCL5 in shaping antigen-specific T cell responses against head and neck cancers. Key objectives include: Investigating how CCL5 chemokine networks impact the development...
- This Project Grant award of $2,223,201.00, funded by the National Institute of Biomedical Imaging and Bioengineering (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health), supports the development of an Augmented Reality (AR) guidance system with deformation modeling to aid in the relocation of tumor margins during head and neck cancer surgery. The project, conducted by Vanderbilt University, aims to improve the success rate of re-resection...
- This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $294,505 to support the development and commercialization of a targeted fluorescence dye for intraoperative imaging and precision surgical treatment of head and neck cancer (HNC). The goal is to create a small peptide-based fluorescent probe that can specifically stain HNC tumors to assist surgeons in identifying tumors...
- This federal Project Grant award of $483,360.00 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will fund research to target vulnerabilities in the EGFR/HER3/HER2 oncogenic signaling circuitry for developing new precision therapies for oral cancer. The project aims to explore synthetic lethal and gene interaction networks to expose druggable systems vulnerabilities and uncover mechanisms of...
This Project Grant award of $452,967.00 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports the development of a novel, robot-integrated system for intraoperative creation and annotation of digital 3D models of resection specimens and the residual tumor bed. The goal is to improve the management of positive surgical margins in the resection of oropharyngeal squamous cell carcinoma, which can lead to reduced local control and overall survival. The proposed solution aims to integrate seamlessly into the transoral-robotic surgery workflow and provide the care team with quantitative margin localization data to improve clinical communication and enable more precise, patient-specific adjuvant therapies. The award was granted to Trustees of Dartmouth College, a prestigious private research university, and has an ultimate completion date of August 14, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $453.0k | 8/15/25 |