This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA 93.173 Research Related to Deafness and Communication Disorders program, provides $149,348 to investigate the biophysical properties of hair cell tip links and their influence on mechanoelectrical transduction (MET) channel function. The project aims to uncover whether the length and calcium-binding-site-mediated flexibility of tip links are important for MET channel...
This federal Project Grant award of $111,513 from the National Institute on Deafness and Other Communication Disorders (CFDA 93.173 - Research Related to Deafness and Communication Disorders) supports a coordinated study of human cochlear anatomy and pathology. The project will use optical coherence tomography (OCT) to image and measure the motion of fresh, unfixed human cochlear structures in their natural state, without invasively accessing the cochlea. This research aims to expand the...
This federal Project Grant award of $781,703, awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA 93.173 "Research Related to Deafness and Communication Disorders", supports research to better understand sensory development in human cochlear organoids. The goals are to define the developmental trajectories of key sensory cell types, test methods to increase the number of hair cells, and accelerate the maturation of hair cells and sensory...
This federal Project Grant award of $673,048 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The objective is to investigate the role of mitochondrial calcium regulation in cochlear hair cells and its contribution to acquired hearing loss, with a focus on assessing the impact of acoustic overstimulation and developing strategies to mitigate noise-induced...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $674,021 to advance the development of an implantable middle-ear microphone system. The award aims to refine and test a prototype microphone, called the UMIC, that can be used in totally-implantable cochlear implants to take advantage of outer-ear acoustic benefits. Key objectives...
This federal Project Grant award of $600,000.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA program "Research Related to Deafness and Communication Disorders" (93.173), supports research on auditory-motor interactions in neural processing and the frequency-following response. The research aims to investigate how the human auditory system balances the competing functions of attenuating self-generated sounds while remaining vigilant...
The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $415,743 Project Grant under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to Oregon Health & Science University (OHSU). The 5-year grant, effective February 1, 2025, will support research to investigate the role of macrophages in the development, homeostasis, and repair of the tympanic membrane (eardrum). The project aims to characterize the origin and function of...
This federal Project Grant award of $610,725.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant will fund research at the University of Pittsburgh to investigate physiological mechanisms that contribute to suprathreshold deficits in speech understanding for individuals with sensorineural hearing loss. The key research activities include:...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $251,856 to New York University from September 1, 2024 to August 31, 2026. The funding supports research investigating the neuroplastic processes underlying early adaptation to cochlear implants, which restore hearing and speech perception in individuals with severe or profound...
The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $115,707 Project Grant under the CFDA 93.173 Research Related to Deafness and Communication Disorders program to the Rector & Visitors of the University of Virginia (UVA). The grant supports research investigating how phospholipid homeostasis regulates hair cell function and health, using mouse models deficient in the phospholipid flippase ATP8B1 or its cofactor TMEM30B. The research aims to uncover the...