This $5.37 million project grant from the National Institutes of Health National Institute on Drug Abuse will fund the development of a context-aware digital adherence intervention called SMARTSTEPS to improve pre-exposure prophylaxis (PrEP) adherence among men who have sex with men with substance use disorder. The grant will support two phases. Phase I will inform the specification of an algorithm that utilizes digital phenotyping data from a smartphone app to anticipate non-adherence based...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports the development and assessment of a behavioral economic intervention to improve HIV-related behaviors among sexual minority men (SMM). The $264,091 award, effective September 15, 2024, aims to refine and evaluate the feasibility and acceptability of an Episodic Future Thinking (EFT) intervention delivered via smartphone to address delayed...
This Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $1,681,276 to the Research Foundation of the City University of New York (RFCUNY) to conduct research on optimizing long-acting injectable (LAI) pre-exposure prophylaxis (PrEP) strategies for sexual minority men (SMM) who use methamphetamine. The study aims to qualitatively identify modifiable care options for LAI PrEP use through rapid interviews,...
This Project Grant award of $2,331,737 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund a comprehensive study to investigate the impact of methamphetamine (MA) use on HIV persistence, immune dysfunction, and clinical outcomes among people living with HIV (PWH) on antiretroviral therapy (ART). The study will leverage three unique cohorts to perform the first-in-human investigations directly quantifying MA concentrations in...
The National Institute on Drug Abuse (NIDA) awarded a $786,979 Project Grant (CFDA 93.279 - Drug Use and Addiction Research Programs) to the University of California, San Diego (UCSD) to implement a two-prong hybrid trial focused on improving identification and treatment of substance use disorder (SUD) among sexual and gender minorities of color (SGMC) in Chicago. The first prong involves implementing routine screening for SUD using the NIDA Quick Screen. The second prong is a social network...
This Project Grant award of $364,832 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support a mentored career development project entitled "Using Implementation Science to Enhance HIV Prevention for Young Men Who Have Sex with Men." The project aims to deliver and evaluate an enhanced care intervention called "HIV Prevention Plus Care (HP+ Care)" at two clinics, which will include motivational...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $405,490 to the University of Georgia Research Foundation, Inc. to characterize chemsex patterns and the adoption of harm reduction measures among men in the southern United States. The key objectives of this 2-year project are to: (1) conduct in-depth interviews with 30 men to examine features of chemsex, such as drug use, sexual...
The federal Project Grant award of $1,272,602.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support the "Integrating U=U into HIV Counseling: A Cluster-Randomized Efficacy Trial (INTUIT 2.0)" research project. The study aims to (1) refine an educational "Undetectable & You" mobile app intervention designed to disseminate information on the prevention benefits of antiretroviral therapy (ART) and...
This Project Grant award of $197,035 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund a 5-year study to design and evaluate a community-based intervention to engage men who use alcohol and substances in HIV prevention services in rural South Africa. The primary objectives are to: 1) explore perceptions and preferences for HIV prevention services among men who frequent local bars (shebeens), 2) develop an intervention...
This Project Grant award, totaling $1,953,293, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The funding supports research to optimize delivery of pre-exposure prophylaxis (PrEP) care for underserved rural people who inject drugs (PWID) in Kentucky. The study will deploy stepped-care adaptive interventions across three rural syringe service programs to identify optimal pathways for increasing PrEP initiation and...
This Project Grant award of $606,924, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports a 2-year research study entitled "CHAMPION - Combining HIV and Stimulant Prevention and Treatment Interventions Optimized for HIV-Negative MSM." The study aims to evaluate the feasibility, acceptability, and preliminary efficacy of a mobile health intervention package that combines a PrEP adherence app with virtual cognitive behavioral therapy to increase PrEP adherence among 100 HIV-negative methamphetamine-using men who have sex with men (MSM). Objectives include assessing PrEP adherence through dried blood spot samples, as well as examining impacts on methamphetamine use and sexual risk behaviors. The study will be conducted by researchers at the University of California, San Diego.