Project Grant R21CA309173
Award Date 4/1/26
Completion Date 3/31/28
Dollars Obligated $421K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92093, USA
Similar Awards
- Federal Grant Award Summary The National Cancer Institute awarded a $661,721 Project Grant to the University of California, San Diego, under the Cancer Biology Research program (CFDA 93.396), effective April 1, 2026 through March 31, 2031. The award supports fundamental research focused on systematic functional mapping and interrogation of intrinsically disordered regions (IDRs) in oncogenic proteins. The research employs high-throughput functional screening technologies and computational...
- Federal Project Grant Award Summary The University of California, San Francisco received a $421,685 Project Grant from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) to investigate discovery methods for identifying functional immune niches within the tumor microenvironment (TME). Awarded on August 8, 2025, with a completion date of July 31, 2027, this research project will deliver scientific discoveries regarding the cellular and molecular mechanisms that...
- Federal Grant Award Summary The National Cancer Institute awarded University of California, San Diego a $699,929 Project Grant on June 20, 2025, under the Cancer Treatment Research program (CFDA 93.395) to enhance immunotherapy response in human papillomavirus negative head and neck squamous cell carcinoma (HPV-HNSCC). The project, which extends through May 31, 2030, focuses on improving dendritic cell (DC) migration to draining sentinel lymph nodes to enhance the efficacy of programmed...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a $615,399 Project Grant to the University of California, Davis under the Cancer Treatment Research program (CFDA 93.395) for the period August 1, 2025, through July 31, 2030. The award supports the development of a transformable nanoparticle (TNP) platform designed to deliver therapeutic peptides and proteins directly to tumor microenvironments on-demand. The TNP technology transforms from nanoparticles to nanofibrils...
- Federal Grant Award Summary The National Cancer Institute awarded a $410,933 Project Grant (Cancer Treatment Research, CFDA 93.395) to the University of California, San Diego, effective March 18, 2026, through February 29, 2028. This exploratory research initiative (R21 mechanism) aims to develop next-generation small interfering RNA (siRNA) therapeutics to treat metastatic castration-resistant prostate cancer (mCRPC). The project focuses on enhancing siRNA delivery into mCRPC tumor cells by...
- Federal Grant Award Summary The National Cancer Institute awarded a $410,115 Project Grant to the University of California, San Diego under the Cancer Biology Research program (CFDA 93.396) for the period August 1, 2025 through July 31, 2027. The award supports research focused on developing improved preclinical models for pancreatic ductal adenocarcinoma (PDAC) by incorporating three-dimensional high-density type I collagen (HDC) scaffolding into tumor cell injection protocols. The research...
- Federal Grant Award Summary The National Cancer Institute awarded Columbia University's Health Sciences Division a $638,120 Project Grant under the Cancer Treatment Research program (CFDA 93.395) effective August 1, 2025, with completion targeted for May 31, 2030. This project develops improved neoantigen cancer vaccine delivery through modulation of microbial vector localization and persistence within the tumor microenvironment. The research utilizes engineered bacterial vectors, such as E....
- Federal Grant Award Summary The University of California, Irvine received a $138,489 Project Grant from the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398) awarded on September 20, 2025, with a completion date of September 19, 2027. The award supports research and development of a methyl arginine targeting chimera (MARTAc) for the lysosomal degradation of intracellular proteins. This project addresses critical limitations of current proteolysis-targeting...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded The Regents of the University of California, San Francisco a Project Grant of $658,722 under the Cancer Treatment Research program (CFDA 93.395) on March 12, 2026, with a completion date of February 28, 2031. The award supports fundamental research to elucidate the mechanisms by which telomerase reverse transcriptase (TERT) promoter mutations drive tumor cell immortality across multiple cancer types. Specifically,...
- Federal Project Grant Award Summary The National Cancer Institute awarded a Project Grant of $677,787 to The Regents of the University of California, San Francisco on August 26, 2025, under the Cancer Treatment Research program (CFDA 93.395) to support a five-year research initiative extending through July 31, 2030. The project, titled "Aire-Expressing Macrophages as Novel Mediators of Tumor Immune Evasion," focuses on identifying and characterizing tolerogenic macrophage populations...