Project Grant R21CA308930
- Summary of Federal Project Grant Award The University of Virginia received a $484,387 Project Grant award from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) on May 7, 2026, with completion targeted for April 30, 2030. This research project delivers novel statistical methodologies and analytical frameworks for the enzyme-linked immunospot (ELISPOT) assay, a widely-used laboratory technique for quantifying cytokine-secreting cells in immunological...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded Virginia Polytechnic Institute & State University a $395,248 Project Grant effective August 11, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct proof-of-concept and feasibility testing of episodic future thinking (EFT) interventions for smoking cessation. This two-year project, concluding July 31, 2027, will develop and evaluate both generalized EFT and cancer-specific EFT approaches...
- Federal Grant Award Summary The National Cancer Institute awarded the University of Virginia a $161,500 Project Grant under the Cancer Biology Research program (CFDA 93.396) effective June 1, 2026, with completion targeted for May 31, 2028. This research initiative develops innovative methodologies for classifying heterogeneous circulating tumor cells (CTCs) from pancreatic ductal adenocarcinoma (PDAC) patients by leveraging single-cell deformability as a complementary metric to traditional...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the University of Virginia a $192,887 Project Grant under the Cancer Research Manpower program (CFDA 93.398) on May 8, 2026, with completion targeted for April 30, 2029. This award supports biomedical research training and investigator development in cancer research aligned with the National Cancer Program's strategic priorities. The grant funds research into sphingolipid-guided stratification and therapeutic opportunities...
- Federal Project Grant Award Summary The National Cancer Institute awarded The MGH Institute of Health Professions, Inc. a $696,498 Project Grant (CFDA 93.393 - Cancer Cause and Prevention Research) effective May 1, 2026, through April 30, 2031, to develop and optimize a multicomponent intervention designed to improve functional recovery and quality of life among breast cancer survivors. The research employs the Multiphase Optimization Strategy (MOST) framework to systematically evaluate three...
- Federal Grant Award Summary The University of Virginia received a $192,888 Project Grant from the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398), effective September 1, 2025, through August 31, 2028. This award supports a novel research initiative designed to identify causal genetic variants associated with colorectal cancer (CRC) risk and elucidate their mechanistic effects through the use of normal colon organoids. The project addresses a critical gap in...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the University of Pittsburgh a $649,620 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) for the period May 1, 2026 through April 30, 2031. This research project addresses gaps in understanding how Medicare Advantage coverage impacts cancer care access, quality, and outcomes for older adults. The study will analyze insurance-related barriers to specialty cancer care by examining coverage...
- Federal Grant Award Summary The National Cancer Institute awarded a $731,503 Project Grant to Sloan-Kettering Institute for Cancer Research, effective June 1, 2026 through May 31, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). The award funds a randomized controlled trial (RCT) evaluating Brief Behavioral Activation for Older Adult Cancer Survivors (BBA-OACS), a telehealth-based psychotherapy intervention designed to address clinically significant depression among...
- Federal Grant Award Summary The National Cancer Institute awarded the University of Virginia a $115,420 Project Grant under the Cancer Research Manpower program (CFDA 93.398) beginning May 1, 2026, with completion targeted for April 30, 2028. This K99/R00 Pathway to Independence Award supports Dr. Kelsey Day's career development as an independent investigator in community-based physical activity research and cancer prevention. During the K99 phase, the award funds four core training...
- Federal Grant Award Summary The University of Virginia received a $2.66 million Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) awarded September 1, 2025, through August 31, 2030. The award supports a coordinated research initiative to develop ceramide-directed therapeutics for acute myeloid leukemia (AML) treatment. The program integrates three inter-related research projects and four essential core facilities to define the biological...
The University of Virginia received a $415,257 Project Grant from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393), effective July 1, 2026 through June 30, 2028. This R21 award supports the development of a comprehensive, adaptive intervention to address financial toxicity (FT) among cancer survivors and caregivers. The project will deliver evidence-based research outputs addressing the multidimensional construct of financial toxicity—encompassing material burden, psychosocial distress, and coping behaviors—which currently affects more than half of cancer survivors and caregivers and contributes to poor survivorship outcomes. The research deliverables include: (1) a landscape confirmation analysis utilizing a 24-member stakeholder advisory team (comprising survivors, caregivers, and supportive care professionals) to identify survivor and caregiver needs and assess existing systems through mixed-methods individual interviews and group meetings; and (2) component prioritization and selection through discrete choice analysis to inform intervention design. The project will culminate in a feasible, evidence-informed intervention framework adaptable to the dynamic trajectories of cancer treatment and recovery, addressing gaps in existing financial toxicity interventions that primarily target only material burden and operate solely during active treatment.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $415.3k | 6/11/26 |