The National Institutes of Health (NIH), through the Trans-NIH Research Support program (CFDA 93.310), awarded a $263,086 Project Grant to the Sloan-Kettering Institute for Cancer Research in New York, NY. This grant will fund the development of a multiparametric ultrasound imaging system and methodology for three-dimensional characterization of the vaginal wall in endometrial cancer patients receiving intravaginal radiation therapy (IVRT). The research aims to identify associations between quantitative ultrasound metrics and clinical assessments of radiation-induced vaginal toxicities, such as stenosis and fibrosis. This novel approach seeks to provide objective measurements of vaginal tissue health, which currently rely on subjective clinician and patient-reported evaluations. If successful, the research could lead to predictive imaging biomarkers that clinicians can use to assess the efficacy of interventions for preventing and treating IVRT-induced vaginal complications.
Generated 2/25/25, 5:19 AM