Project Grant R21AI202005
- The National Institute of Allergy and Infectious Diseases awarded Colorado State University $174,488 on March 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate transmission dynamics and fitness of St. Louis encephalitis virus (SLEV) in mosquito vectors and the role of West Nile virus immunity in avian reservoirs. The research examines why contemporary SLEV strains traced to South America have reemerged in the western United States since 2015 after...
- The National Institute of Allergy and Infectious Diseases awarded Colorado State University $2,036,679 on September 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct high-throughput screening and characterization of small-molecule inhibitors targeting N-terminal autoproteolysis of coronavirus main protease precursors. The recipient will develop and execute cell-based assays to identify compounds that selectively interfere with precursor-mediated...
- The National Institute of Allergy and Infectious Diseases awarded Colorado State University $423,500 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate bacteriophage interactions with nontuberculous mycobacteria in mammalian cell intracellular environments. The research addresses the therapeutic use of bacteriophages—naturally occurring viruses that infect and kill bacteria—as an alternative treatment for drug-resistant nontuberculous...
- The National Institute of Allergy and Infectious Diseases awarded the Board of Regents of the University of Nebraska $436,157 on April 6, 2026, through the Allergy and Infectious Diseases Research program (CFDA 93.855) to reassess West Nile Virus action thresholds for improved disease control. The University of Nebraska Medical Center in Omaha, Nebraska, will conduct research to determine how variability in West Nile Virus RNA quantities detected in mosquito surveillance pools—measured by...
- The National Institute of Allergy and Infectious Diseases awarded Kansas State University $738,183 on July 20, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to characterize the immunoregulatory protease network that controls melanization in Anopheles gambiae, the African malaria mosquito vector. The research identifies molecular interactions that regulate phenoloxidase activation and melanization cascade proteases, with the objective of understanding how protease...
- The National Institute of Allergy and Infectious Diseases awarded Kennesaw State University $517,956 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the effects of per- and polyfluoroalkyl substances (PFAS) on mosquito fitness and arbovirus transmission potential. The recipient will establish laboratory models of sublethal PFAS exposure across four mosquito species: Aedes albopictus (Zika virus vector), Aedes aegypti (Zika virus...
- The National Institute of Allergy and Infectious Diseases awarded New Mexico State University $146,671 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 3, 2026, for a project grant (R16AI201108) investigating the link between immunometabolism and epigenetics in the malaria vector mosquito Anopheles stephensi. The project employs a multi-omics approach integrating metabolomic, epigenomic, and transcriptomic data to establish mechanistic linkages between...
- The National Institute of Allergy and Infectious Diseases, operating under the Department of Health and Human Services, awarded Kansas State University $238,247 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on larval immunity in the African malaria mosquito Anopheles gambiae. The project identifies molecular interactions that regulate melanization through proteolytic activation of phenoloxidase in An. gambiae larvae, with the...
- Federal Project Grant Award Summary Colorado State University received a $437,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The award supports research to understand Plasmodium vivax transmission networks through the development and application of novel microhaplotype and kinship analysis methodologies. The project will employ...
- The National Institute of Allergy and Infectious Diseases (a component of the Department of Health and Human Services National Institutes of Health) awarded $713,873 to The Regents of The University of Colorado (University of Colorado-Denver) on May 21, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855, assistance type Project Grant R01AI198189). The award funds research to define mechanistically how discrete lymph node stromal cells regulate viral dissemination to...
The National Institute of Allergy and Infectious Diseases awarded Colorado State University $192,500 on August 19, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the role of enteroendocrine cells in West Nile Virus replication and transmission in Culex tarsalis mosquitoes. The research comprises two aims: Aim 1 will use dissociated midgut cells from colonized mosquitoes infected with barcoded WNV, flow cytometry, and sequencing to quantify the impact of enteroendocrine cells and other midgut cell types on WNV load and population diversity; Aim 2 will employ RNAi to experimentally manipulate enteroendocrine cell abundance in the midgut to measure effects on mosquito blood feeding and salivation, thereby assessing WNV transmission potential. The work integrates cellular, molecular, and behavioral analyses to examine how specific midgut cell types may shape WNV transmission dynamics and arbovirus exploitation of host biology. Colorado State University's Sponsored Programs division, operating as a public land-grant research institution, is the recipient. Performance occurs in Fort Collins, Colorado, with a period of performance from August 19, 2026, through July 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $192.5k | 8/20/26 |