Project Grant R21AI199805
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a Project Grant of $576,501 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, with completion scheduled for July 31, 2030. This research project investigates the previously uncharacterized role of nucleoprotein (NP) exoribonuclease in Lassa virus (LASV) replication and fitness. The award...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $440,000 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Texas Medical Branch at Galveston for a two-year project period (August 1, 2025 – July 31, 2027). This Project Grant funds biomedical research investigating the pathogenic mechanisms of rickettsioses, devastating human infections that disproportionately affect microvascular...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a $520,128 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning August 1, 2025, with completion scheduled for July 31, 2030. This research initiative investigates molecular mechanisms by which Ehrlichia chaffeensis, the causative agent of human monocytotropic ehrlichiosis, manipulates host cell RNA...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $463,698 to the University of Texas Medical Branch at Galveston on June 11, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct preclinical studies on the repurposing of FDA-approved adenosine A2A receptor (A2AR) antagonists for treating lethal rickettsial infections. The project, spanning through May 31, 2030, will deliver mechanistic research...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $440,000 in Project Grant funding under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Texas Medical Branch at Galveston, effective July 3, 2025, through June 30, 2027. This award supports research to determine the function and mechanism of long non-coding RNA CHAST in Trypanosoma cruzi infection and dissemination, which causes Chagas disease. The...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a Project Grant of $489,965 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period September 1, 2025, through August 31, 2026. This research project, titled "IFN/SOCS1 Signaling During Post-Influenza Bacterial Infection," will investigate the mechanisms by which interferon (IFN) signaling and...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $451,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025, through June 30, 2027. This award supports the development and utilization of a humanized lung-on-a-chip model to investigate nontuberculous mycobacteria (NTM) infections in a physiologically relevant...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a $2.92 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 1, 2025, through August 31, 2029. This award supports fundamental research investigating norovirus capsid dynamics and adaptive immune evasion mechanisms. The research utilizes a mouse norovirus model system to elucidate...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Health Science Center at Houston $418,360 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 11, 2025, for a project concluding July 31, 2027. This Project Grant funds systematic analysis of Treponema pallidum gene expression under host infection-related conditions to advance understanding of syphilis pathogenesis and inform vaccine...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $415,000 Project Grant to The University of Texas Southwestern Medical Center on May 7, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The five-year project, scheduled for completion by April 30, 2031, delivers investigator-initiated biomedical research aimed at establishing mechanistic insights into a novel cell cycle regulator complex for cancer therapy...
The University of Texas Medical Branch at Galveston received a $444,125 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 12, 2026, with a completion date of May 31, 2028. The award funds investigator-initiated biomedical research examining the role of long non-coding ribonucleic acids (lncRNAs) in modulating host immunity and pathogen survival during Orientia tsutsugamushi infection, which causes scrub typhus—an emerging, life-threatening zoonotic disease that has recently expanded geographically beyond the traditional Asia-Pacific region into North America. The research project will deliver scientific knowledge products addressing two primary objectives: (1) determining the expression profile of lncRNAs during Orientia infection in a host- and cell-type-specific manner, and (2) investigating the regulatory function of a novel lncRNA, NONMMUT105897.1, in macrophage-mediated immunity and bacterial clearance. Through RNA sequencing and functional studies, the project will advance understanding of scrub typhus pathogenesis mechanisms and host immune modulation, with potential applications for vaccine development and therapeutic interventions for this emerging infectious disease with high mortality rates and limited treatment options.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $444.1k | 6/16/26 |