Project Grant R21AI199669
- Federal Project Grant Award Summary Award Overview The National Institute of Allergy and Infectious Diseases (NIAID) awarded Emory University a Project Grant of $954,603 on April 9, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award funds research and development activities extending through March 31, 2028, conducted at Emory's Atlanta, Georgia location. Research Deliverables The grant supports the development of a novel long-acting injectable...
- Federal Grant Award Summary Award Overview: Emory University's Office of Sponsored Programs received a $234,156 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 28, 2026, with completion targeted for October 31, 2028. The award funds research conducted in Atlanta, Georgia. Research Products and Services: The grant supports fundamental research on capsid assembly...
- Federal Project Grant Summary Emory University received a $273,000 exploratory project grant awarded May 8, 2026, through the National Institute of Allergy and Infectious Diseases (NIAID) Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research investigating the role of B cells and antibody responses in virus-induced hepatocellular carcinoma (HCC) using a physiological rodent model of chronic hepaciviral infection. The primary deliverables include establishment...
- Federal Project Grant Award Summary Emory University received a $909,998 project grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 5, 2026, with completion targeted for January 31, 2031. The research focuses on characterizing an antiretroviral drug therapy (ART)-free approach to establishing a simian immunodeficiency virus (SIV) reservoir through antibody-mediated mechanisms. The...
- Federal Project Grant Award Summary Emory University received a $909,998 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 5, 2026, with completion targeted for April 30, 2031. The project aims to develop an innovative HIV vaccination strategy utilizing DNA-lipid nanoparticle (DNA-LNP) technology to induce strong and durable cellular and humoral immunity against HIV. The...
- Federal Project Grant Award Summary Emory University received a $160,448 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded March 10, 2026, with completion targeted for September 10, 2028. The research will generate scientific products addressing antiviral resistance to acyclic phosphonates in orthopoxviruses, specifically monkeypox virus (MPXV). The project will deliver three...
- Federal Grant Award Summary Emory University received a $2,297,892 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 17, 2025, with completion targeted for June 30, 2029. The award funds a four-year research investigation into the mechanisms by which interferon-induced transmembrane proteins (IFITMs) inhibit viral membrane fusion and restrict diverse enveloped viruses...
- Federal Project Grant Award Summary Emory University's Office of Sponsored Programs received a $430,375 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, with completion scheduled for July 31, 2027. The award funds investigator-initiated biomedical research examining inter-membrane lipid signaling mechanisms in gram-negative bacteria, specifically focusing on...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Rockefeller University $862,748 through the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 23, 2026, to support research on elucidating host and viral determinants of treatment response in chronic Hepatitis B virus (HBV) infection. The five-year project, scheduled for completion on January 31, 2031, focuses on understanding the biological mechanisms that...
- Federal Grant Award Summary HBVTech, LLC received a $258,750 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of September 1, 2025, and completion target of August 31, 2026. The grant supports the development of HBVZ10, a novel gene therapy candidate designed to cure chronic hepatitis B virus (HBV) infection. HBVZ10 utilizes an optimized adeno-associated virus serotype...
Emory University received a $249,225 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on June 23, 2026, with completion targeted for May 31, 2028. This award supports research characterizing potent antiviral compounds that target the hepatitis B virus (HBV) capsid, specifically focusing on a novel class of bivalent capsid assembly modulators (CAMs)—dual-compound antivirals connected by a linker—that demonstrate sub-nanomolar potency against HBV. The research aims to elucidate how bivalent CAMs induce distinct structural changes and lattice deformations of HBV capsids, addressing a critical gap in understanding this emerging therapeutic approach. The project addresses the substantial global health burden of chronic HBV infection affecting over 295 million people worldwide by developing antivirals targeting alternative steps in the HBV replication cycle beyond current nucleoside reverse transcriptase inhibitors and interferon-alpha treatments. Current therapies fail to eliminate covalently closed circular DNA (ccDNA), necessitating lifelong treatment. By characterizing the mechanisms through which bivalent CAMs disrupt capsid assembly and function, the research supports the development of next-generation antivirals that could enable functional HBV cure and reduce the worldwide economic burden of chronic infection management.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.2k | 6/23/26 |