Project Grant R61AI197036
- Federal Grant Award Summary Emory University received a $482,017 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 18, 2025, with completion targeted for June 30, 2026. The research project, "Investigating the Role of Intrahepatic Plasma Cells in the Clearance of HCV Infection: Implications for Rational Vaccine Design," seeks to elucidate the mechanistic origins of...
- Federal Grant Award Summary Emory University received a $922,840 Project Grant awarded February 2, 2026, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated biomedical research on inducible hepatic-associated lymphoid tissue (IHALT) and long-lived plasma cell (LLPC) generation and maintenance. The research extends through January 31, 2031, and will be performed at Emory's...
- Federal Project Grant Award Summary Orlance, Inc., a woman-owned small business based in Seattle, Washington, received a $300,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of September 11, 2025, and completion date of August 31, 2027. The award supports the development of a therapeutic nucleic acid vaccine targeting chronic hepatitis B (CHB) in individuals...
- Federal Project Grant Award Summary Emory University received a $909,998 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 5, 2026, with a completion date of January 31, 2031. The research project focuses on characterizing antibody-mediated approaches to establish a Simian Immunodeficiency Virus (SIV) reservoir in the absence of antiretroviral drug therapy. The primary...
- Federal Project Grant Award Summary Emory University was awarded $234,156 on February 28, 2026, through the National Institute of Allergy and Infectious Diseases (NIAID) Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on capsid assembly mechanisms of Kaposi Sarcoma Associated Herpesvirus (KSHV). The research project, scheduled for completion by October 31, 2028, will deliver scientific knowledge and methodological advances regarding herpesvirus capsid...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Emory University $653,693 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a project grant effective May 12, 2025 through April 30, 2027. The award supports structural research on HIV-1 virions and investigation of the capsid-targeting antiviral compound lenacapavir. The project employs single-particle cryo-electron microscopy (cryo-EM), cryo-electron tomography,...
- Federal Project Grant Award Summary Emory University's Office of Sponsored Programs received a $430,375 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, with completion scheduled for July 31, 2027. The award funds investigator-initiated biomedical research examining inter-membrane lipid signaling mechanisms in gram-negative bacteria, specifically focusing on...
- Federal Grant Award Summary HBVtech, LLC received a $258,750 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 1, 2025 through August 31, 2026. The award supports development of HBVZ10, a novel hepatitis B virus (HBV) cure therapy candidate utilizing gene therapy technology. The primary deliverable is the advancement of a development strategy to obtain...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Scripps Research Institute a $899,741 Project Grant effective April 1, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports research and development of a long-acting injectable (LAI) therapy for hepatitis B virus (HBV) treatment in individuals co-infected with human immunodeficiency virus (HIV), addressing a significant...
- Federal Project Grant Award Summary Emory University received a $1,332,155 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 10, 2025, with a completion date of May 31, 2030. The grant supports systematic research to optimize broadly neutralizing antibody (BNAb) immunotherapies combined with antiretroviral therapy (ART) for HIV cure in infants with perinatal infection, with...
Emory University received a $954,603 project grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded April 9, 2026, with completion targeted for March 31, 2028. The award funds the development of a biodegradable and biocompatible nanoparticle injectable sterile formulation that encapsulates ALG-001075, a novel capsid assembly modulator with pan-genotypic activity against hepatitis B virus (HBV). This formulation is designed to enable prolonged drug release, extending dosing intervals from daily administration to monthly or longer intervals, thereby improving medication adherence and reducing treatment costs for individuals with chronic hepatitis B infection, including those co-infected with HIV/HBV. The research addresses a critical clinical need by leveraging ALG-001075's exceptional potency and dual anti-HBV mechanism—disrupting capsid assembly while impeding transcription and de novo formation of covalently closed circular DNA (cccDNA)—to create a long-acting therapeutic option. The sustained-release formulation will be particularly beneficial for low-resource settings and populations with limited access to daily oral antivirals, offering improved drug efficacy while reducing adherence-related treatment failures and overall healthcare costs associated with chronic HBV management.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $954.6k | 4/9/26 |