Project Grant R21AI199072
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $678,218 Project Grant to the University of Maryland, Baltimore, effective April 1, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports multi-omics research investigating bacterial-host interactions between the filarial nematode Brugia malayi and its obligate Wolbachia bacterial endosymbiont. The research...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of Maryland, Baltimore a $463,676 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 7, 2025, with completion targeted for July 31, 2030. This research initiative will generate scientific knowledge and methodological advances focused on understanding Fc-mediated effector functions in infectious disease contexts, specifically...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $455,500 Project Grant to the University of Maryland, Baltimore under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 3, 2026, with a completion date of January 31, 2028. This award supports investigator-initiated research to characterize cord-blood-specific gamma-delta T cells and elucidate their functional heterogeneity in neonates and infants. The research...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of Maryland, Baltimore $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 6, 2026, with completion targeted for March 31, 2028. This project grant funds research to develop predictive models of vaginal microbiome composition and bacterial vaginosis (BV) recurrence. The research employs whole-genome shotgun metagenomic sequencing...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant totaling $155,893 to the University of Maryland, Baltimore under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 24, 2026, with a completion date of March 31, 2031. This award supports investigator-initiated research to generate experimental data clarifying the pathology of Mycoplasma genitalium (MG), an emerging sexually transmitted pathogen, and to...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park $417,295 on February 23, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated biomedical research on heme sensing and adaptation mechanisms in Group A Streptococcus (GAS). This R21 Project Grant, with a completion date of January 31, 2028, will deliver fundamental research findings on how GAS...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of Maryland, Baltimore $136,988 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated biomedical research on Enterovirus D68 (EV-D68) infection mechanisms. The award, obligated on August 20, 2025, with a project completion date of July 31, 2027, supports research designed to advance scientific understanding of how transcription...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park $421,720 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 2, 2026, with a completion date of January 31, 2028. This Project Grant supports basic research characterizing the activation of NLRP11 (nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 11) inflammasome by mycobacterial...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant of $426,938 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 23, 2025, with a completion date of May 31, 2027. The award supports the development of a simplified, cost-effective mouse model of chronic Mycobacterium abscessus lung disease using BALB/c mice that requires only weekly cyclophosphamide administration. This...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, Baltimore a Project Grant totaling $466,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 1, 2026, with a completion date of January 31, 2031. This research grant funds a comprehensive investigation into the relationship between gut microbial protein metabolism and oral immunotherapy (OIT) efficacy in pediatric food...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $194,375 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Maryland, Baltimore, effective May 12, 2026, through April 30, 2028. The award supports the development and characterization of a novel in vitro model system utilizing human nasal organoids derived from pediatric adenoid and tonsil tissues to study Bordetella pertussis (whooping cough) infection and mucosal immune response mechanisms. The research deliverables include: (1) comprehensive characterization and validation of pediatric adenoid- and tonsil-derived organoids with comparative analysis to native resected tissue to establish model fidelity, development of autologous immune organoid co-cultures incorporating tissue-resident immune cells; and (2) systematic examination of B. pertussis infection processes in the organoid models across dose- and time-dependent parameters, including assessment of bacterial invasion, replication, and shedding, as well as characterization of innate and adaptive immune cell responses. This research addresses critical knowledge gaps regarding pertussis pathogenesis and immune response in the pediatric upper respiratory mucosa, the most vulnerable population affected by this disease, to advance understanding of vaccine efficacy and inform development of improved preventive strategies.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $194.4k | 5/12/26 |