Project Grant R21AI195332
- Federal Project Grant Award Summary The University of Texas Health Science Center at Houston received a $429,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 2, 2026, with completion targeted for January 31, 2028. This research project delivers spatial transcriptional analysis technology and methodologies focused on investigating gene expression in fungal infections,...
- Federal Grant Award Summary Prokaryotics Incorporated received a $299,697 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 19, 2025, with a completion date of August 31, 2026. The award supports the development of a mechanistically novel antifungal agent targeting fks1 and cell wall 1-3-D-glucan biosynthesis to address life-threatening fungal infections in hospital...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the Regents of the University of Michigan a $411,078 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2028. The award supports research to identify novel antifungal compounds derived from symbiotic bacteria—microorganisms that co-exist with and provide benefits to eukaryotic hosts—with the objective of...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $1,193,457 to the University of Massachusetts Medical School on July 21, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop fungal antigen resources for vaccines and diagnostics. This collaborative project, executed through a consortium involving UMass Chan, the University of Texas at San Antonio (UTSA), and the University of Wisconsin-Milwaukee...
- Federal Project Grant Award Summary Texas A&M University System Health Science Center received a $624,267 Project Grant award (CFDA 93.855, Allergy and Infectious Diseases Research) from the National Institute of Allergy and Infectious Diseases on August 11, 2025, with a completion date of July 31, 2030. The research initiative focuses on developing methods to understand how small molecule compounds penetrate the cellular envelope of gram-negative bacteria, particularly Acinetobacter...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of California, Davis a $441,204 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on preventing invasive candidiasis caused by Candida albicans. The award, issued February 13, 2026, with a completion date of January 31, 2028, funds biomedical research aimed at understanding and preventing systemic fungal infections in...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh a $437,250 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research on unrecognized azole resistance among Candida parapsilosis causing bloodstream infections. The award, effective February 1, 2026 through January 31, 2028, supports investigator-initiated biomedical research addressing infectious disease mechanisms and...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh a $437,250 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 1, 2026, through January 31, 2028. This investigator-initiated research project delivers scientific investigation into Candida glabrata populations during gastrointestinal tract colonization and intra-abdominal candidiasis (IAC), with particular...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Stony Brook University $782,178 through the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 12, 2025, for a project extending through May 31, 2030. The award supports the development of novel antifungal therapeutic agents targeting sterylglucosidases, enzymes critical to fungal pathogenesis. The research builds upon prior work demonstrating that deletion of the...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital a $489,500 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, with completion targeted for July 31, 2027. This award funds biomedical research aimed at identifying and characterizing novel antifungal drug targets within Candida albicans cell wall stress response pathways. The research focuses on the Target...
Texas A&M University System Health Science Center received a $192,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on June 1, 2026, with completion scheduled for May 31, 2028. The award supports a two-year research initiative focused on developing novel antifungal therapeutics to combat multi-drug-resistant fungal infections, specifically targeting Candida auris and Candida albicans. The project delivers research products and validation services centered on structure-based design, synthesis, and testing of small molecule inhibitors (SMIs) that target fungal SEC14 phosphatidylinositol transfer proteins (SEC14 PITPs). Under Aim 1, the research team will conduct fragment-based screening and synthesis of next-generation SMIs that disrupt phosphoinositide (PIP) signaling pathways critical to fungal viability and virulence. Aim 2 encompasses an in vitro and in vivo validation platform utilizing purified fungal SEC14 PITPs and pathogenized yeast systems to assess SMI potencies and target specificities. The research addresses an urgent public health need identified by the Centers for Disease Control and Prevention regarding invasive fungal infections, with potential broad-spectrum applications against additional fungal pathogens beyond the primary Candida species studied.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $192.5k | 4/17/26 |